YRC Public Data Repository - Protein Structure Prediction

Protein:	GLO2_ECOLI
Organism:	Escherichia coli
Length:	251 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLO2_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|91223497, gi\|... - gi\|91223497\|ref\|ZP_01258762.1\| putative hydroxyacylglutathione hydrolase GloB [Vibrio alginolyticus ...	248.0	[0..1]	[251..2]
gi\|116190165, gi... - gi\|75831264\|ref\|ZP_00760529.1\| COG0491: Zn-dependent hydrolases, including glyoxylases [Vibrio chole... GLO2_VIBC3 - Hydroxyacylglutathione hydrolase OS=Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa... gi\|121726557, gi... - gi\|75817019\|ref\|ZP_00747475.1\| COG0491: Zn-dependent hydrolases, including glyoxylases [Vibrio chole... GLO2_VIBCM - Hydroxyacylglutathione hydrolase OS=Vibrio cholerae serotype O1 (strain M66-2) GN=gloB PE=3 SV=1 gi\|229355194, gi... - gi\|229507689\|ref\|ZP_04397194.1\| hydroxyacylglutathione hydrolase [Vibrio cholerae BX 330286], gi\|229... gi\|183179464, gi... - gi\|183179464\|ref\|ZP_02957675.1\| hydroxyacylglutathione hydrolase GloB, putative [Vibrio cholerae MZO... gi\|229519251, gi... - gi\|229519251\|ref\|ZP_04408694.1\| hydroxyacylglutathione hydrolase [Vibrio cholerae RC9], gi\|229343940... gi\|229522183, gi... - gi\|229522183\|ref\|ZP_04411600.1\| hydroxyacylglutathione hydrolase [Vibrio cholerae TM 11079-80], gi\|2... gi\|229332534, gi... - gi\|229528760\|ref\|ZP_04418150.1\| hydroxyacylglutathione hydrolase [Vibrio cholerae 12129(1)], gi\|2293... gi\|229607193, gi... - gi\|229607193\|ref\|YP_002877841.1\| hydroxyacylglutathione hydrolase [Vibrio cholerae MJ-1236], gi\|2293... gi\|121549549, gi... - gi\|121586283\|ref\|ZP_01676073.1\| hydroxyacylglutathione hydrolase GloB, putative [Vibrio cholerae 274... gi\|254286455, gi... - gi\|254286455\|ref\|ZP_04961412.1\| hydroxyacylglutathione hydrolase GloB, putative [Vibrio cholerae AM-... gi\|153213781, gi... - gi\|153213781\|ref\|ZP_01948989.1\| hydroxyacylglutathione hydrolase GloB, putative [Vibrio cholerae 158... gi\|124119800, gi... - gi\|153221271\|ref\|ZP_01952286.1\| hydroxyacylglutathione hydrolase GloB, putative [Vibrio cholerae MAK... gi\|148874588, gi... - gi\|153829953\|ref\|ZP_01982620.1\| putative hydroxyacylglutathione hydrolase GloB [Vibrio cholerae 623-... gi\|153825354, gi... - gi\|153825354\|ref\|ZP_01978021.1\| hydroxyacylglutathione hydrolase GloB, putative [Vibrio cholerae MZO... gi\|153817113, gi... - gi\|153817113\|ref\|ZP_01969780.1\| hydroxyacylglutathione hydrolase GloB, putative [Vibrio cholerae NCT... gi\|153820855, gi... - gi\|229512116\|ref\|ZP_04401595.1\| hydroxyacylglutathione hydrolase [Vibrio cholerae B33], gi\|229352081... GLO2_VIBCH - Hydroxyacylglutathione hydrolase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N1... GLO2_VIBCH - Hydroxyacylglutathione hydrolase OS=Vibrio cholerae GN=gloB PE=3 SV=1	247.0	[0..1]	[251..2]
gi\|75856799, gi\|... - gi\|75856799\|ref\|ZP_00764422.1\| COG0491: Zn-dependent hydrolases, including glyoxylases [Vibrio sp. E...	247.0	[0..1]	[251..9]
GLO2_VIBPA - Hydroxyacylglutathione hydrolase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=... gi\|149746730, gi... - gi\|153839746\|ref\|ZP_01992413.1\| hydroxyacylglutathione hydrolase [Vibrio parahaemolyticus AQ3810], g... GLO2_VIBPA - Hydroxyacylglutathione hydrolase OS=Vibrio parahaemolyticus GN=gloB PE=3 SV=1	246.0	[0..1]	[251..2]
tr\|D7HE21\|D7HE21... - Hydroxyacylglutathione hydrolase OS=Vibrio cholerae RC385 GN=gloB PE=3 SV=1 gi\|116218207, gi... - gi\|75824349\|ref\|ZP_00753806.1\| COG0491: Zn-dependent hydrolases, including glyoxylases [Vibrio chole...	246.0	[0..1]	[251..2]
gi\|254225773, gi... - gi\|75820871\|ref\|ZP_00750909.1\| COG0491: Zn-dependent hydrolases, including glyoxylases [Vibrio chole...	246.0	[0..1]	[251..2]
gi\|90437139, gi\|... - gi\|90581655\|ref\|ZP_01237444.1\| putative hydroxyacylglutathione hydrolase GloB [Vibrio angustum S14],...	245.0	[0..1]	[251..2]
gi\|89075028, gi\|... - gi\|89075028\|ref\|ZP_01161473.1\| putative hydroxyacylglutathione hydrolase GloB [Photobacterium sp. SK...	244.0	[0..1]	[251..2]
GLO2_VIBVU - Hydroxyacylglutathione hydrolase OS=Vibrio vulnificus GN=gloB PE=3 SV=1 GLO22_VIBVY - Hydroxyacylglutathione hydrolase 2 OS=Vibrio vulnificus (strain YJ016) GN=gloB2 PE=3 SV=1 GLO2_VIBVU - Hydroxyacylglutathione hydrolase OS=Vibrio vulnificus (strain CMCP6) GN=gloB PE=3 SV=1	243.0	[0..1]	[251..2]
gi\|59712545, gi\|... - gi\|59712545\|ref\|YP_205321.1\| hydroxyacylglutathione hydrolase [Vibrio fischeri ES114], gi\|59480646\|g...	241.0	[0..1]	[251..2]

Back

Predicted Domain #1

Region A:
Residues: [1-251]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLNSIPAFD DNYIWVLNDE AGRCLIVDPG DAEPVLNAIA ANNWQPEAIF LTHHHHDHVG  60
   61 GVKELVEKFP QIVVYGPQET QDKGTTQVVK DGETAFVLGH EFSVIATPGH TLGHICYFSK 120
  121 PYLFCGDTLF SGGCGRLFEG TASQMYQSLK KLSALPDDTL VCCAHEYTLS NMKFALSILP 180
  181 HDLSINDYYR KVKELRAKNQ ITLPVILKNE RQINVFLRTE DIDLINVINE ETLLQQPEER 240
  241 FAWLRSKKDR F

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.045757
Match:	2qedA
Description:	No description for 2qedA was found.

Predicted functions:

Term	Confidence	Notes
hydroxyacylglutathione hydrolase activity	3.53012507604564	bayes_pls_golite062009
catalytic activity	0.941400907161877	bayes_pls_golite062009
binding	0.900972948435178	bayes_pls_golite062009
thiolester hydrolase activity	0.802604883362264	bayes_pls_golite062009
hydrolase activity	0.021392930321391	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: