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Catalysis of the hydrolysis of any ester bond. Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate. Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: hydroxyacylglutathione hydrolase activity
Acc: GO:0004416
Aspect: Molecular Function
Desc: Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.
Synonyms:
  • acetoacetylglutathione hydrolase activity
  • glyoxalase II activity
  • S-2-hydroxylacylglutathione hydrolase activity
  • S-(2-hydroxyacyl)glutathione hydrolase activity
Proteins in PDR annotated with:
   This term: 25 [Search]
   Term or descendants: 25 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004416 - hydroxyacylglutathione hydrolase activity (interactive image map)
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