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View Structure Prediction Details

Protein: PGK1_PANTR
Organism: Pan troglodytes
Length: 417 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PGK1_PANTR.

Description E-value Query
Range		 Subject
Range
gi|197099640 - gi|197099640|ref|NP_001127126.1| phosphoglycerate kinase 1 [Pongo abelii]
PGK1_PONPY - Phosphoglycerate kinase 1 (EC 2.7.2.3) - Pongo pygmaeus (Orangutan)
 0.0 [1..417] [1..417]
PGK1_PONAB - Phosphoglycerate kinase 1 OS=Pongo abelii GN=PGK1 PE=2 SV=4
PGK1_MACFA - Phosphoglycerate kinase 1 OS=Macaca fascicularis GN=PGK1 PE=2 SV=3
PGK1_PONPY - Phosphoglycerate kinase 1 - Pongo pygmaeus (Orangutan)
gi|109131308 - gi|109131308|ref|XP_001100787.1| PREDICTED: similar to phosphoglycerate kinase 1 isoform 4 [Macaca m...
 0.0 [1..417] [1..417]
gi|61354676 - gi|61354676|gb|AAX41039.1| phosphoglycerate kinase 1 [synthetic construct]
 0.0 [1..417] [1..417]
gi|48145549 - gi|48145549|emb|CAG32997.1| PGK1 [Homo sapiens]
 0.0 [1..417] [1..417]
gi|55250521 - gb|AAH86210.1| Unknown (protein for MGC:98689) [Xenopus laevis]
PGK1_MOUSE - Phosphoglycerate kinase 1 OS=Mus musculus GN=Pgk1 PE=1 SV=4
 0.0 [1..417] [1..417]
PGK1_CRIGR - Phosphoglycerate kinase 1 OS=Cricetulus griseus GN=PGK1 PE=2 SV=2
 0.0 [1..417] [1..417]
PGK1_RAT - Phosphoglycerate kinase 1 OS=Rattus norvegicus GN=Pgk1 PE=1 SV=2
 0.0 [1..417] [1..417]

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Predicted Domain #1
Region A:
Residues: [1-417] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSNKLTLD KLDVKGKRVV MRVDFNVPMK NNQITNNQRI KAAVPSIKFC LDNGAKSVVL  60
   61 MSHLGRPDGV PMPDKYSLEP VAVELKSLLG KDVLFLKDCV GPEVEKACAN PAAGSVILLE 120
  121 NLRFHVEEEG KGKDASGNKV KAEPAKIEAF RASLSKLGDV YVNDAFGTAH RAHSSMVGVN 180
  181 LPQKAGGFLM KKELNYFAKA LESPERPFLA ILGGAKVADK IQLINNMLDK VNEMIIGGGM 240
  241 AFTFLKVLNN MEIGTSLFDE EGAKIVKDLM SKAEKNGVKI TLPVDFVTAD KFDENAKTGQ 300
  301 ATVASGIPAG WMGLDCGPES SKKYAEAVTR AKQIVWNGPV GVFEWEAFAR GTKALMDEVV 360
  361 KATSRGCITI IGGGDTATCC AKWNTEDKVS HVSTGGGASL ELLEGKVLPG VDALSNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1vjcA
Description: Structure of pig muscle PGK complexed with MgATP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoglycerate kinase activity 5.4060222740811 bayes_pls_golite062009
kinase activity 5.10875323814482 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.75644406547116 bayes_pls_golite062009
transferase activity 3.84971620558441 bayes_pls_golite062009
catalytic activity 2.30057758519011 bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor 2.28472985705972 bayes_pls_golite062009
binding 2.00400587462181 bayes_pls_golite062009
ATP binding 1.2270597395465 bayes_pls_golite062009
adenyl ribonucleotide binding 1.19223643201287 bayes_pls_golite062009
adenyl nucleotide binding 1.17740080861612 bayes_pls_golite062009
transcription regulator activity 0.9898248694651 bayes_pls_golite062009
ribonucleotide binding 0.946046256290779 bayes_pls_golite062009
purine ribonucleotide binding 0.943434082819351 bayes_pls_golite062009
purine nucleotide binding 0.936146648259702 bayes_pls_golite062009
nucleotide binding 0.931721122227797 bayes_pls_golite062009
protein binding 0.206093694938779 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle