YRC Public Data Repository - Protein Structure Prediction

Protein:	FUCP_ECOLI
Organism:	Escherichia coli
Length:	438 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUCP_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|60467752, gi\|... - gi\|60467752\|gb\|EAL65769.1\| hypothetical protein DDB0191430 [Dictyostelium discoideum], gi\|29500764\|g... gi\|60467752, gi\|... - gi\|66810832\|ref\|XP_639123.1\| major facilitator superfamily transporter [Dictyostelium discoideum AX4...	217.0	[0..19]	[417..595]
gi\|46107656, gi\|... - gi\|46107656\|ref\|XP_380887.1\| hypothetical protein FG00711.1 [Gibberella zeae PH-1], gi\|42547814\|gb\|E...	212.0	[0..3]	[407..1422]
gi\|70725707, gi\|... - gi\|70725707\|ref\|YP_252621.1\| hypothetical protein SH0706 [Staphylococcus haemolyticus JCSC1435], gi\|...	211.0	[0..24]	[416..179]
gi\|110827356, gi... - gi\|111615223\|ref\|ZP_01402289.1\| Sugar phosphate permease-like [Verminephrobacter eiseniae EF01-2], g...	184.0	[0..20]	[435..296]
gi\|90205974, gi\|... - gi\|90205974\|ref\|ZP_01208611.1\| Drug resistance transporter EmrB/QacA subfamily [Mycobacterium vanbaa...	184.0	[0..14]	[397..58]
gi\|78495751, gi\|... - gi\|78495751\|ref\|ZP_00847969.1\| Major facilitator superfamily MFS_1 [Rhodopseudomonas palustris BisB1...	183.0	[0..1]	[436..424]
gi\|39944294, gi\|... - gi\|39944294\|ref\|XP_361684.1\| hypothetical protein MGG_04158 [Magnaporthe grisea 70-15], gb\|EAA50399....	181.0	[0..10]	[433..121]
gi\|68389434 - gi\|68389434\|ref\|XP_691920.1\| PREDICTED: similar to solute carrier family 17 (sodium-dependent inorga...	178.0	[0..22]	[432..141]
gi\|58701069 - gi\|58701069\|gb\|AAW81281.1\| permease of the major facilitator superfamily-like [Lactobacillus paracas...	176.0	[0..20]	[407..2]
gi\|89336117, gi\|... - gi\|89896669\|ref\|YP_520156.1\| hypothetical protein DSY3923 [Desulfitobacterium hafniense Y51], gi\|893...	175.0	[0..10]	[434..8]

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Predicted Domain #1

Region A:
Residues: [1-438]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNTSIQTQS YRAVDKDAGQ SRSYIIPFAL LCSLFFLWAV ANNLNDILLP QFQQAFTLTN  60
   61 FQAGLIQSAF YFGYFIIPIP AGILMKKLSY KAGIITGLFL YALGAALFWP AAEIMNYTLF 120
  121 LVGLFIIAAG LGCLETAANP FVTVLGPESS GHFRLNLAQT FNSFGAIIAV VFGQSLILSN 180
  181 VPHQSQDVLD KMSPEQLSAY KHSLVLSVQT PYMIIVAIVL LVALLIMLTK FPALQSDNHS 240
  241 DAKQGSFSAS LSRLARIRHW RWAVLAQFCY VGAQTACWSY LIRYAVEEIP GMTAGFAANY 300
  301 LTGTMVCFFI GRFTGTWLIS RFAPHKVLAA YALIAMALCL ISAFAGGHVG LIALTLCSAF 360
  361 MSIQYPTIFS LGIKNLGQDT KYGSSFIVMT IIGGGIVTPV MGFVSDAAGN IPTAELIPAL 420
  421 CFAVIFIFAR FRSQTATN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.69897
Match:	1pw4A
Description:	Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate transmembrane transporter activity	3.16484357749134	bayes_pls_golite062009
sugar transmembrane transporter activity	2.77541159976289	bayes_pls_golite062009
transporter activity	2.54286095434601	bayes_pls_golite062009
sugar:hydrogen symporter activity	2.21878849047485	bayes_pls_golite062009
cation:sugar symporter activity	2.21878849047485	bayes_pls_golite062009
transmembrane transporter activity	2.01247278444729	bayes_pls_golite062009
monosaccharide transmembrane transporter activity	1.85936140095795	bayes_pls_golite062009
substrate-specific transporter activity	1.77039368764865	bayes_pls_golite062009
solute:hydrogen symporter activity	1.68455852928739	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.66673693200184	bayes_pls_golite062009
hexose phosphate transmembrane transporter activity	0.771603913181441	bayes_pls_golite062009
glucose-6-phosphate transmembrane transporter activity	0.771603913181441	bayes_pls_golite062009
active transmembrane transporter activity	0.33203350453105	bayes_pls_golite062009
polyol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.24475883286552	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.2309068592963	bayes_pls_golite062009
ion transmembrane transporter activity	0.18188709249385	bayes_pls_golite062009
binding	0.105551689569449	bayes_pls_golite062009
glycerol-3-phosphate transmembrane transporter activity	1.26964387230144E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: