YRC Public Data Repository - Protein Structure Prediction

Protein:	FLAW_ECOLI
Organism:	Escherichia coli
Length:	173 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FLAW_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|117622892, gi... - gi\|117622892\|ref\|YP_851805.1\| flavodoxin FldA [Escherichia coli APEC O1], gi\|115512016\|gb\|ABJ00091.1... gi\|237707346, gi... - gi\|237707346\|ref\|ZP_04537827.1\| flavodoxin FldA [Escherichia sp. 3_2_53FAA], gi\|226898556\|gb\|EEH8481... gi\|26246661, gi\|... - gi\|26246661\|ref\|NP_752701.1\| flavodoxin [Escherichia coli CFT073], gi\|26107060\|gb\|AAN79244.1\|AE01675... gi\|157065844, gi... - gi\|157160164\|ref\|YP_001457482.1\| flavodoxin FldA [Escherichia coli HS], gi\|157065844\|gb\|ABV05099.1\| ... gi\|188495523, gi... - gi\|188495523\|ref\|ZP_03002793.1\| flavodoxin [Escherichia coli 53638], gi\|188490722\|gb\|EDU65825.1\| fla... gi\|157157770, gi... - gi\|157157770\|ref\|YP_001461848.1\| flavodoxin FldA [Escherichia coli E24377A], gi\|157079800\|gb\|ABV1950... gi\|91071301, gi\|... - gi\|91209727\|ref\|YP_539713.1\| flavodoxin FldA [Escherichia coli UTI89], gi\|91071301\|gb\|ABE06182.1\| fl... gi\|110804679, gi... - gi\|110804679\|ref\|YP_688199.1\| flavodoxin FldA [Shigella flexneri 5 str. 8401], gi\|110614227\|gb\|ABF02...	176.0	[0..1]	[168..40]
gi\|21104364 - gi\|21104364\|dbj\|BAB93452.1\| flavodoxin [Actinobacillus actinomycetemcomitans]	174.0	[0..3]	[169..4]
gi\|37525294, gi\|... - gi\|37525294\|ref\|NP_928638.1\| flavodoxin FldA [Photorhabdus luminescens subsp. laumondii TTO1], gi\|36...	173.0	[0..3]	[169..4]
gi\|42629140 - gi\|42629140\|ref\|ZP_00154689.1\| COG0716: Flavodoxins [Haemophilus influenzae R2846] gi\|42630494 - gi\|42630494\|ref\|ZP_00156033.1\| COG0716: Flavodoxins [Haemophilus influenzae R2866] gi\|144983098 - gi\|144983098\|gb\|EDJ90598.1\| flavodoxin [Haemophilus influenzae R3021] FLAV_HAEIN - Flavodoxin OS=Haemophilus influenzae GN=fldA PE=3 SV=2 gi\|148827330, gi... - gi\|148827330\|ref\|YP_001292083.1\| flavodoxin FldA [Haemophilus influenzae PittGG], gi\|148718572\|gb\|AB... FLAV_HAEIN - Flavodoxin OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=fldA PE=3 SV=2 gi\|148825543, gi... - gi\|148825543\|ref\|YP_001290296.1\| flavodoxin FldA [Haemophilus influenzae PittEE], gi\|148715703\|gb\|AB... gi\|145271120, gi... - gi\|145639752\|ref\|ZP_01795354.1\| flavodoxin [Haemophilus influenzae PittII], gi\|145271120\|gb\|EDK11035... gi\|68056995, gi\|... - gi\|68248796\|ref\|YP_247908.1\| flavodoxin FldA [Haemophilus influenzae 86-028NP], gi\|68056995\|gb\|AAX87... gi\|145267099, gi... - gi\|145635626\|ref\|ZP_01791323.1\| flavodoxin [Haemophilus influenzae PittAA], gi\|145267099\|gb\|EDK07106... gi\|229811894, gi... - gi\|229845183\|ref\|ZP_04465317.1\| flavodoxin FldA [Haemophilus influenzae 6P18H1], gi\|229811894\|gb\|EEP... gi\|229847366, gi... - gi\|229847366\|ref\|ZP_04467467.1\| flavodoxin FldA [Haemophilus influenzae 7P49H1], gi\|229809692\|gb\|EEP... gi\|144985371, gi... - gi\|145633800\|ref\|ZP_01789524.1\| flavodoxin [Haemophilus influenzae 3655], gi\|144985371\|gb\|EDJ92201.1... gi\|145631313 - gi\|145631313\|ref\|ZP_01787085.1\| flavodoxin [Haemophilus influenzae 22.4-21] gi\|145628492, gi... - gi\|145628492\|ref\|ZP_01784292.1\| flavodoxin [Haemophilus influenzae 22.1-21], gi\|144978962\|gb\|EDJ8864...	173.0	[0..3]	[169..4]
gi\|33519785, gi\|... - gi\|33519785\|ref\|NP_878617.1\| flavodoxin FldA [Candidatus Blochmannia floridanus], gi\|33504130\|emb\|CA...	173.0	[0..1]	[169..1]
gi\|146317300, gi... - gi\|75827406\|ref\|ZP_00756841.1\| COG0716: Flavodoxins [Vibrio cholerae O395], gi\|227118546\|ref\|YP_0028... gi\|90074876 - gi\|90074876\|dbj\|BAE87115.1\| flavodoxin 1 [Vibrio cholerae bv. albensis] gi\|15642099, gi\|... - gi\|9656648\|gb\|AAF95245.1\| flavodoxin 1 [Vibrio cholerae O1 biovar El Tor str. N16961], gi\|15642099\|r... gi\|11250201 - pir\|\|A82120 flavodoxin [similarity] - Vibrio cholerae (strain N16961 serogroup O1) gi\|153831270, gi... - gi\|153831270\|ref\|ZP_01983937.1\| flavodoxin 1 [Vibrio cholerae 623-39], gi\|148873250\|gb\|EDL71385.1\| f... gi\|227082225, gi... - gi\|227082225\|ref\|YP_002810776.1\| flavodoxin 1 [Vibrio cholerae M66-2], gi\|227010113\|gb\|ACP06325.1\| f... gi\|229355317, gi... - gi\|229507812\|ref\|ZP_04397317.1\| flavodoxin 1 [Vibrio cholerae BX 330286], gi\|229355317\|gb\|EEO20238.1... gi\|229511951, gi... - gi\|229511951\|ref\|ZP_04401430.1\| flavodoxin 1 [Vibrio cholerae B33], gi\|229351916\|gb\|EEO16857.1\| flav... gi\|254844891, gi... - gi\|254849186\|ref\|ZP_05238536.1\| flavodoxin FldA [Vibrio cholerae MO10], gi\|254844891\|gb\|EET23305.1\| ... gi\|229348935, gi... - gi\|229513754\|ref\|ZP_04403216.1\| flavodoxin 1 [Vibrio cholerae TMA 21], gi\|229348935\|gb\|EEO13892.1\| f... gi\|229519087, gi... - gi\|229519087\|ref\|ZP_04408530.1\| flavodoxin 1 [Vibrio cholerae RC9], gi\|229343776\|gb\|EEO08751.1\| flav... gi\|229522056, gi... - gi\|229522056\|ref\|ZP_04411473.1\| flavodoxin 1 [Vibrio cholerae TM 11079-80], gi\|229340981\|gb\|EEO05986... gi\|229524105, gi... - gi\|229524105\|ref\|ZP_04413510.1\| flavodoxin 1 [Vibrio cholerae bv. albensis VL426], gi\|229337686\|gb\|E... gi\|229332659, gi... - gi\|229528885\|ref\|ZP_04418275.1\| flavodoxin 1 [Vibrio cholerae 12129(1)], gi\|229332659\|gb\|EEN98145.1\|... gi\|229607357, gi... - gi\|229607357\|ref\|YP_002878005.1\| flavodoxin 1 [Vibrio cholerae MJ-1236], gi\|229370012\|gb\|ACQ60435.1\|...	173.0	[0..2]	[169..3]
gi\|52424915, gi\|... - gi\|52424915\|ref\|YP_088052.1\| flavodoxin FldA [Mannheimia succiniciproducens MBEL55E], gi\|52306967\|gb...	173.0	[0..3]	[169..4]
gi\|51595472, gi\|... - gi\|51595472\|ref\|YP_069663.1\| flavodoxin FldA [Yersinia pseudotuberculosis IP 32953], gi\|51588754\|emb... gi\|45435770, gi\|... - gi\|45440912\|ref\|NP_992451.1\| flavodoxin FldA [Yersinia pestis biovar Microtus str. 91001], gi\|454357... gi\|16122846, gi\|... - gi\|218929714\|ref\|YP_002347589.1\| flavodoxin FldA [Yersinia pestis CO92], gi\|16122846\|ref\|NP_406159.1... gi\|162353342, gi... - gi\|77635344\|ref\|ZP_00797430.1\| COG0716: Flavodoxins [Yersinia pestis Angola], gi\|162420527\|ref\|YP_00... gi\|153950369, gi... - gi\|77632088\|ref\|ZP_00794674.1\| COG0716: Flavodoxins [Yersinia pseudotuberculosis IP 31758], gi\|15395... gi\|89102764 - gi\|89102764\|ref\|ZP_01175375.1\| COG0716: Flavodoxins [Yersinia pestis biovar Orientalis str. IP275] gi\|108808456, gi... - gi\|108808456\|ref\|YP_652372.1\| flavodoxin FldA [Yersinia pestis Antiqua], gi\|108780369\|gb\|ABG14427.1\|... gi\|108774932, gi... - gi\|229901525\|ref\|ZP_04516647.1\| flavodoxin 1 [Yersinia pestis Nepal516], gi\|229681454\|gb\|EEO77548.1\|... gi\|22125111, gi\|... - gi\|22125111\|ref\|NP_668534.1\| flavodoxin FldA [Yersinia pestis KIM], gi\|21957968\|gb\|AAM84785.1\|AE0137... gi\|25282827 - pir\|\|AF0321 flavodoxin 1 [imported] - Yersinia pestis (strain CO92) gi\|165922807, gi... - gi\|165925200\|ref\|ZP_02221032.1\| flavodoxin 1 [Yersinia pestis biovar Orientalis str. F1991016], gi\|1... gi\|166212562, gi... - gi\|166212562\|ref\|ZP_02238597.1\| flavodoxin 1 [Yersinia pestis biovar Antiqua str. B42003004], gi\|166... gi\|166008499, gi... - gi\|166008499\|ref\|ZP_02229397.1\| flavodoxin 1 [Yersinia pestis biovar Antiqua str. E1979001], gi\|1659... gi\|167422533, gi... - gi\|167422533\|ref\|ZP_02314286.1\| flavodoxin 1 [Yersinia pestis biovar Orientalis str. MG05-1020], gi\|... gi\|167050879, gi... - gi\|167398375\|ref\|ZP_02303899.1\| flavodoxin 1 [Yersinia pestis biovar Antiqua str. UG05-0454], gi\|167... gi\|167467957 - gi\|167467957\|ref\|ZP_02332661.1\| flavodoxin 1 [Yersinia pestis FV-1] gi\|167057296, gi... - gi\|167423126\|ref\|ZP_02314879.1\| flavodoxin 1 [Yersinia pestis biovar Mediaevalis str. K1973002], gi\|... gi\|229694551, gi... - gi\|229838185\|ref\|ZP_04458344.1\| flavodoxin 1 [Yersinia pestis biovar Orientalis str. PEXU2], gi\|2296... gi\|229895974, gi... - gi\|229895974\|ref\|ZP_04511144.1\| flavodoxin 1 [Yersinia pestis Pestoides A], gi\|229700897\|gb\|EEO88926... gi\|229898704, gi... - gi\|229898704\|ref\|ZP_04513849.1\| flavodoxin 1 [Yersinia pestis biovar Orientalis str. India 195], gi\|... Q66DC1\|Q66DC1_YERPS - Flavodoxin 1 - Yersinia pseudotuberculosis gi\|149365466, gi... - gi\|149365466\|ref\|ZP_01887501.1\| flavodoxin 1 [Yersinia pestis CA88-4125], gi\|149291879\|gb\|EDM41953.1... gi\|186894503, gi... - gi\|186894503\|ref\|YP_001871615.1\| flavodoxin FldA [Yersinia pseudotuberculosis PB1/+], gi\|186697529\|g... gi\|145211578, gi... - gi\|145599882\|ref\|YP_001163958.1\| flavodoxin FldA [Yersinia pestis Pestoides F], gi\|145211578\|gb\|ABP4... gi\|170025212, gi... - gi\|170025212\|ref\|YP_001721717.1\| flavodoxin FldA [Yersinia pseudotuberculosis YPIII], gi\|169751746\|g...	172.0	[0..2]	[169..3]
gi\|15602218, gi\|... - gi\|15602218\|ref\|NP_245290.1\| flavodoxin FldA [Pasteurella multocida subsp. multocida str. Pm70], gi\|...	172.0	[0..3]	[169..4]
gi\|83584542 - gi\|83584542\|ref\|ZP_00923216.1\| COG0716: Flavodoxins [Escherichia coli 101-1]	172.0	[0..1]	[168..6]

Back

Predicted Domain #1

Region A:
Residues: [1-173]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMGLFYGSS TCYTEMAAEK IRDIIGPELV TLHNLKDDSP KLMEQYDVLI LGIPTWDFGE  60
   61 IQEDWEAVWD QLDDLNLEGK IVALYGLGDQ LGYGEWFLDA LGMLHDKLST KGVKFVGYWP 120
  121 TEGYEFTSPK PVIADGQLFV GLALDETNQY DLSDERIQSW CEQILNEMAE HYA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.0
Match:	1ag9A
Description:	Flavodoxin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity	2.0467816962267	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	1.85486974695416	bayes_pls_golite062009
binding	0.681337940863521	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor	0.650874844500866	bayes_pls_golite062009
catalytic activity	0.275631658558537	bayes_pls_golite062009
coenzyme binding	0.265571968246766	bayes_pls_golite062009
protein binding	0.251879151875848	bayes_pls_golite062009
FMN binding	0.056297096581433	bayes_pls_golite062009
cofactor binding	0.0451815885965905	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: