YRC Public Data Repository - Protein Structure Prediction

Protein:	FEPB_ECOLI
Organism:	Escherichia coli
Length:	318 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FEPB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|20806884 - gi\|20806884\|ref\|NP_622055.1\| ABC-type Fe3+-siderophores transport systems, periplasmic components [T... gi\|20806884, gi\|... - gi\|20806884\|ref\|NP_622055.1\| ABC-type Fe3+-siderophores transport systems, periplasmic components [T...	234.0	[0..1]	[318..14]
gi\|166857129, gi... - gi\|76795368\|ref\|ZP_00777741.1\| Periplasmic binding protein [Thermoanaerobacter ethanolicus ATCC 3322... gi\|241903823, gi... - gi\|241903823\|ref\|ZP_04788540.1\| periplasmic binding protein [Thermoanaerobacter brockii subsp. finni...	227.0	[0..15]	[318..17]
gi\|114843982, gi... - gi\|167040563\|ref\|YP_001663548.1\| periplasmic binding protein [Thermoanaerobacter sp. X514], gi\|16685...	227.0	[0..15]	[318..17]
gi\|208737029, gi... - gi\|208822836\|ref\|ZP_03263154.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding peripla... gi\|208815479, gi... - gi\|208815479\|ref\|ZP_03256658.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding peripla... gi\|217320677, gi... - gi\|217324456\|ref\|ZP_03440540.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding peripla... gi\|209398102, gi... - gi\|209398102\|ref\|YP_002269226.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding peripl... gi\|189369196, gi... - gi\|189403828\|ref\|ZP_02785269.2\| ferrienterobactin ABC transporter, ferrienterobactin-binding peripla... gi\|189357939, gi... - gi\|189402014\|ref\|ZP_02779696.2\| ferrienterobactin ABC transporter, ferrienterobactin-binding peripla... gi\|208727594, gi... - gi\|208807793\|ref\|ZP_03250130.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding peripla... gi\|195936140 - gi\|195936140\|ref\|ZP_03081522.1\| iron-enterobactin transporter periplasmic binding protein [Escherich... gi\|189003043, gi... - gi\|189003043\|gb\|EDU72029.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding periplasmic... gi\|187769686, gi... - gi\|187769686\|gb\|EDU33530.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding periplasmic... gi\|189379330, gi... - gi\|189379330\|gb\|EDU97746.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding periplasmic... gi\|189373533, gi... - gi\|189373533\|gb\|EDU91949.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding periplasmic... gi\|254591159, gi... - gi\|254791759\|ref\|YP_003076596.1\| iron-enterobactin transporter subunit, periplasmic-binding componen... gi\|168770192, gi... - gi\|189360899\|gb\|EDU79318.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding periplasmic... gi\|15829885, gi\|... - gi\|15829885\|ref\|NP_308658.1\| iron-enterobactin transporter periplasmic binding protein [Escherichia ... gi\|168747740, gi... - gi\|188017735\|gb\|EDU55857.1\| ferrienterobactin ABC transporter, ferrienterobactin-binding periplasmic... gi\|209777532, gi... - pir\|\|G90707 hypothetical protein ECs0631 [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|15829885, gi\|... - gi\|15829885\|ref\|NP_308658.1\| ferric enterobactin (enterochelin) binding protein periplasmic componen...	225.0	[0..1]	[318..1]
gi\|89085832, gi\|... - gi\|89099446\|ref\|ZP_01172322.1\| YvrC [Bacillus sp. NRRL B-14911], gi\|89085832\|gb\|EAR64957.1\| YvrC [Ba...	224.0	[0..1]	[317..33]
gi\|12513485, gi\|... - gi\|15800307\|ref\|NP_286319.1\| iron-enterobactin transporter periplasmic binding protein [Escherichia ... gi\|25303204 - pir\|\|C85558 hypothetical protein fepB [imported] - Escherichia coli (strain O157:H7, substrain EDL9...	224.0	[0..1]	[318..1]
gi\|81244449, gi\|... - gi\|82543038\|ref\|YP_406985.1\| iron-enterobactin transporter periplasmic binding protein [Shigella boy...	216.0	[0..1]	[318..1]
gi\|5457942, gi\|1... - gi\|5457942\|emb\|CAB49432.1\| Iron (III) ABC transporter, periplasmic-binding protein, putative [Pyroco... gi\|7521157, gi\|5... - pir\|\|A75169 probable iron (III) ABC transporter, periplasmic-binding protein PAB0349 - Pyrococcus ab...	215.0	[0..3]	[315..1]
gi\|81240020, gi\|... - gi\|82775872\|ref\|YP_402219.1\| iron-enterobactin transporter periplasmic binding protein [Shigella dys...	215.0	[0..1]	[318..1]

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Predicted Domain #1

Region A:
Residues: [1-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLAPLYRNA LLLTGLLLSG IAAVQAADWP RQITDSRGTH TLESQPQRIV STSVTLTGSL  60
   61 LAIDAPVIAS GATTPNNRVA DDQGFLRQWS KVAKERKLQR LYIGEPSAEA VAAQMPDLIL 120
  121 ISATGGDSAL ALYDQLSTIA PTLIINYDDK SWQSLLTQLG EITGHEKQAA ERIAQFDKQL 180
  181 AAAKEQIKLP PQPVTAIVYT AAAHSANLWT PESAQGQMLE QLGFTLAKLP AGLNASQSQG 240
  241 KRHDIIQLGG ENLAAGLNGE SLFLFAGDQK DADAIYANPL LAHLPAVQNK QVYALGTETF 300
  301 RLDYYSAMQV LDRLKALF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.0
Match:	2chuA
Description:	No description for 2chuA was found.

Predicted functions:

Term	Confidence	Notes
transporter activity	2.12407655395775	bayes_pls_golite062009
siderophore transporter activity	2.06074201308788	bayes_pls_golite062009
siderophore-iron transmembrane transporter activity	1.8612171704528	bayes_pls_golite062009
transmembrane transporter activity	1.71565596749022	bayes_pls_golite062009
active transmembrane transporter activity	1.18061423605374	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.13141267190653	bayes_pls_golite062009
primary active transmembrane transporter activity	1.12707873013446	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	1.12215201014266	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	1.12215201014266	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	1.12176509475129	bayes_pls_golite062009
ATPase activity, coupled	0.82644963270613	bayes_pls_golite062009
substrate-specific transporter activity	0.75988725183257	bayes_pls_golite062009
ATPase activity	0.69786001264916	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.6571215031711	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.64772242476987	bayes_pls_golite062009
pyrophosphatase activity	0.62286698166539	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.61399064290254	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.61327477119588	bayes_pls_golite062009
binding	0.491558239542048	bayes_pls_golite062009
ion transmembrane transporter activity	0.45143591778596	bayes_pls_golite062009
cation transmembrane transporter activity	0.36419556786484	bayes_pls_golite062009
catalytic activity	0.130495772245536	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: