YRC Public Data Repository - Protein Structure Prediction

Protein:	FEPA_ECOLI
Organism:	Escherichia coli
Length:	746 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FEPA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|1778500 - gi\|1778500\|gb\|AAB40783.1\| ferrienterobactin receptor precursor [Escherichia coli]	439.0	[0..1]	[746..21]
gi\|75210786, gi\|... - gi\|75210786\|ref\|ZP_00710918.1\| COG4771: Outer membrane receptor for ferrienterochelin and colicins [...	436.0	[0..1]	[746..1]
gi\|75258679, gi\|... - gi\|75258679\|ref\|ZP_00730086.1\| COG4771: Outer membrane receptor for ferrienterochelin and colicins [...	436.0	[0..1]	[746..1]
gi\|157157247, gi... - gi\|75189623\|ref\|ZP_00702890.1\| COG4771: Outer membrane receptor for ferrienterochelin and colicins [... gi\|209917840, gi... - gi\|209917840\|ref\|YP_002291924.1\| outer membrane receptor FepA [Escherichia coli SE11], gi\|209911099\|...	436.0	[0..1]	[746..1]
gi\|82775861, gi\|... - gi\|82775861\|ref\|YP_402208.1\| outer membrane receptor FepA [Shigella dysenteriae Sd197], gi\|81240009\|...	436.0	[0..1]	[746..1]
gi\|237707444, gi... - gi\|237707444\|ref\|ZP_04537925.1\| outer membrane receptor FepA [Escherichia sp. 3_2_53FAA], gi\|2268986... gi\|91071203, gi\|... - gi\|91209629\|ref\|YP_539615.1\| outer membrane receptor FepA [Escherichia coli UTI89], gi\|91071203\|gb\|A... gi\|215485627, gi... - gi\|215485627\|ref\|YP_002328058.1\| outer membrane receptor FepA [Escherichia coli O127:H6 str. E2348/6... gi\|26106960, gi\|... - gi\|26246561\|ref\|NP_752600.1\| outer membrane receptor FepA [Escherichia coli CFT073], gi\|26106960\|gb\|...	435.0	[0..1]	[746..1]
gi\|218553126, gi... - gi\|218553126\|ref\|YP_002386039.1\| outer membrane receptor FepA [Escherichia coli IAI1], gi\|218359894\|... gi\|218694024, gi... - gi\|218694024\|ref\|YP_002401691.1\| outer membrane receptor FepA [Escherichia coli 55989], gi\|218350756... gi\|75236566, gi\|... - gi\|75236566\|ref\|ZP_00720654.1\| COG4771: Outer membrane receptor for ferrienterochelin and colicins [... gi\|75229531, gi\|... - gi\|75229531\|ref\|ZP_00716078.1\| COG4771: Outer membrane receptor for ferrienterochelin and colicins [...	435.0	[0..1]	[746..1]
gi\|110614121, gi... - gi\|110804573\|ref\|YP_688093.1\| outer membrane receptor FepA [Shigella flexneri 5 str. 8401], gi\|11061...	435.0	[0..1]	[746..1]
gi\|157065757, gi... - gi\|75194768\|ref\|ZP_00704838.1\| COG4771: Outer membrane receptor for ferrienterochelin and colicins [...	435.0	[0..1]	[746..1]
gi\|74311118, gi\|... - gi\|74311118\|ref\|YP_309537.1\| outer membrane receptor FepA [Shigella sonnei Ss046], gi\|73854595\|gb\|AA...	435.0	[0..1]	[746..1]

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Predicted Domain #1

Region A:
Residues: [1-746]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKKIHSLAL LVNLGIYGVA QAQEPTDTPV SHDDTIVVTA AEQNLQAPGV STITADEIRK  60
   61 NPVARDVSKI IRTMPGVNLT GNSTSGQRGN NRQIDIRGMG PENTLILIDG KPVSSRNSVR 120
  121 QGWRGERDTR GDTSWVPPEM IERIEVLRGP AAARYGNGAA GGVVNIITKK GSGEWHGSWD 180
  181 AYFNAPEHKE EGATKRTNFS LTGPLGDEFS FRLYGNLDKT QADAWDINQG HQSARAGTYA 240
  241 TTLPAGREGV INKDINGVVR WDFAPLQSLE LEAGYSRQGN LYAGDTQNTN SDSYTRSKYG 300
  301 DETNRLYRQN YALTWNGGWD NGVTTSNWVQ YEHTRNSRIP EGLAGGTEGK FNEKATQDFV 360
  361 DIDLDDVMLH SEVNLPIDFL VNQTLTLGTE WNQQRMKDLS SNTQALTGTN TGGAIDGVST 420
  421 TDRSPYSKAE IFSLFAENNM ELTDSTIVTP GLRFDHHSIV GNNWSPALNI SQGLGDDFTL 480
  481 KMGIARAYKA PSLYQTNPNY ILYSKGQGCY ASAGGCYLQG NDDLKAETSI NKEIGLEFKR 540
  541 DGWLAGVTWF RNDYRNKIEA GYVAVGQNAV GTDLYQWDNV PKAVVEGLEG SLNVPVSETV 600
  601 MWTNNITYML KSENKTTGDR LSIIPEYTLN STLSWQARED LSMQTTFTWY GKQQPKKYNY 660
  661 KGQPAVGPET KEISPYSIVG LSATWDVTKN VSLTGGVDNL FDKRLWRAGN AQTTGDLAGA 720
  721 NYIAGAGAYT YNEPGRTWYM SVNTHF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	115.0
Match:	1fepA
Description:	Ferric enterobactin receptor FepA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
siderophore transporter activity	3.55322460883158	bayes_pls_golite062009
siderophore-iron transmembrane transporter activity	3.3599194515452	bayes_pls_golite062009
ferric iron transmembrane transporter activity	3.15788151414187	bayes_pls_golite062009
iron ion transmembrane transporter activity	3.11842604500047	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	2.94864336338952	bayes_pls_golite062009
transporter activity	2.60507547654721	bayes_pls_golite062009
heme transporter activity	2.15516892820591	bayes_pls_golite062009
metal ion transmembrane transporter activity	1.83774407491961	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.66917553837297	bayes_pls_golite062009
cofactor transporter activity	1.63125627644933	bayes_pls_golite062009
cation transmembrane transporter activity	1.62350870078795	bayes_pls_golite062009
ion transmembrane transporter activity	1.59970461150566	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.51901351867178	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.18512826739631	bayes_pls_golite062009
substrate-specific transporter activity	0.86109425700917	bayes_pls_golite062009
transmembrane transporter activity	0.424956094980482	bayes_pls_golite062009
binding	0.195879338858333	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: