YRC Public Data Repository - Protein Structure Prediction

Protein:	FECA_ECOLI
Organism:	Escherichia coli
Length:	774 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FECA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194437740, gi... - gi\|83586665\|ref\|ZP_00925297.1\| COG4772: Outer membrane receptor for Fe3+-dicitrate [Escherichia coli... gi\|218372983, gi... - gi\|218702997\|ref\|YP_002410626.1\| ferric citrate outer membrane transporter; KpLE2 phage-like element...	442.0	[0..1]	[774..1]
gi\|57903206 - gi\|57903206\|gb\|AAL08456.2\|AF326777_31 FecA [Shigella flexneri 2a]	440.0	[0..1]	[774..1]
gi\|145922 - gi\|145922\|gb\|AAA23760.1\| iron dicitrate transport protein precursor	440.0	[0..1]	[774..1]
gi\|75189001, gi\|... - gi\|75189001\|ref\|ZP_00702268.1\| COG4772: Outer membrane receptor for Fe3+-dicitrate [Escherichia coli...	440.0	[0..1]	[774..1]
gi\|83570539, gi\|... - gi\|83570539\|ref\|ZP_00921983.1\| COG4772: Outer membrane receptor for Fe3+-dicitrate [Shigella dysente...	439.0	[0..1]	[774..1]
gi\|81243484, gi\|... - gi\|82779336\|ref\|YP_405685.1\| citrate-dependent iron transport, outer membrane receptor [Shigella dys...	439.0	[0..1]	[774..1]
gi\|190902829, gi... - gi\|75229680\|ref\|ZP_00716213.1\| COG4772: Outer membrane receptor for Fe3+-dicitrate [Escherichia coli...	439.0	[0..1]	[774..1]
gi\|194426672, gi... - gi\|75212165\|ref\|ZP_00712205.1\| COG4772: Outer membrane receptor for Fe3+-dicitrate [Escherichia coli...	439.0	[0..1]	[774..1]
gi\|75235422, gi\|... - gi\|75235422\|ref\|ZP_00719630.1\| COG4772: Outer membrane receptor for Fe3+-dicitrate [Escherichia coli...	437.0	[0..1]	[774..1]

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Predicted Domain #1

Region A:
Residues: [1-774]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPLRVFRKT TPLVNTIRLS LLPLAGLSFS AFAAQVNIAP GSLDKALNQY AAHSGFTLSV  60
   61 DASLTRGKQS NGLHGDYDVE SGLQQLLDGS GLQVKPLGNN SWTLEPAPAP KEDALTVVGD 120
  121 WLGDARENDV FEHAGARDVI RREDFAKTGA TTMREVLNRI PGVSAPENNG TGSHDLAMNF 180
  181 GIRGLNPRLA SRSTVLMDGI PVPFAPYGQP QLSLAPVSLG NMDAIDVVRG GGAVRYGPQS 240
  241 VGGVVNFVTR AIPQDFGIEA GVEGQLSPTS SQNNPKETHN LMVGGTADNG FGTALLYSGT 300
  301 RGSDWREHSA TRIDDLMLKS KYAPDEVHTF NSLLQYYDGE ADMPGGLSRA DYDADRWQST 360
  361 RPYDRFWGRR KLASLGYQFQ PDSQHKFNIQ GFYTQTLRSG YLEQGKRITL SPRNYWVRGI 420
  421 EPRYSQIFMI GPSAHEVGVG YRYLNESTHE MRYYTATSSG QLPSGSSPYD RDTRSGTEAH 480
  481 AWYLDDKIDI GNWTITPGMR FEHIESYQNN AITGTHEEVS YNAPLPALNV LYHLTDSWNL 540
  541 YANTEGSFGT VQYSQIGKAV QSGNVEPEKA RTWELGTRYD DGALTAEMGL FLINFNNQYD 600
  601 SNQTNDTVTA RGKTRHTGLE TQARYDLGTL TPTLDNVSIY ASYAYVNAEI REKGDTYGNL 660
  661 VPFSPKHKGT LGVDYKPGNW TFNLNSDFQS SQFADNANTV KESADGSTGR IPGFMLWGAR 720
  721 VAYDFGPQMA DLNLAFGVKN IFDQDYFIRS YDDNNKGIYA GQPRTLYMQG SLKF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	123.0
Match:	1kmoA
Description:	Outer membrane transporter FecA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cofactor transporter activity	4.41227788916596	bayes_pls_golite062009
transporter activity	4.15398171369398	bayes_pls_golite062009
heme transporter activity	3.56934074076046	bayes_pls_golite062009
substrate-specific transporter activity	2.43332676180972	bayes_pls_golite062009
transmembrane transporter activity	1.99898520864149	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.37880749517427	bayes_pls_golite062009
ion transmembrane transporter activity	0.9810521942815	bayes_pls_golite062009
porin activity	0.896682978257159	bayes_pls_golite062009
cation transmembrane transporter activity	0.89213734347785	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.70757821289609	bayes_pls_golite062009
binding	0.643879907209189	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.60516455096546	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.17491456011246	bayes_pls_golite062009
lipid transporter activity	0.10911346172326	bayes_pls_golite062009
protein binding	0.0112080975548029	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: