YRC Public Data Repository - Protein Structure Prediction

Protein:	DNAA_ECOLI
Organism:	Escherichia coli
Length:	467 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DNAA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|30043271, gi\|... - gi\|30065010\|ref\|NP_839181.1\| chromosomal replication initiation protein [Shigella flexneri 2a str. 2...	387.0	[0..1]	[467..1]
gi\|15833891, gi\|... - gi\|15833891\|ref\|NP_312664.1\| chromosomal replication initiation protein [Escherichia coli O157:H7 st... gi\|208819691, gi... - gi\|208819691\|ref\|ZP_03260011.1\| chromosomal replication initiator protein DnaA [Escherichia coli O15... DNAA_ECO5E - Chromosomal replication initiator protein DnaA OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN... gi\|217325750, gi... - gi\|217325750\|ref\|ZP_03441834.1\| chromosomal replication initiator protein DnaA [Escherichia coli O15... gi\|25299840, gi\|... - pir\|\|G86054 replication initiation protein DnaA [similarity] - Escherichia coli (strain O157:H7, sub... gi\|168798737, gi... - gi\|189378776\|gb\|EDU97192.1\| chromosomal replication initiator protein DnaA [Escherichia coli O157:H7... gi\|195936323 - gi\|195936323\|ref\|ZP_03081705.1\| chromosomal replication initiation protein [Escherichia coli O157:H7... gi\|208727477, gi... - gi\|208807676\|ref\|ZP_03250013.1\| chromosomal replication initiator protein DnaA [Escherichia coli O15... gi\|12518541, gi\|... - gi\|15804296\|ref\|NP_290335.1\| chromosomal replication initiation protein [Escherichia coli O157:H7 ED... gi\|208811867, gi... - gi\|208811867\|ref\|ZP_03253196.1\| chromosomal replication initiator protein DnaA [Escherichia coli O15... gi\|168759888, gi... - gi\|189369914\|gb\|EDU88330.1\| chromosomal replication initiator protein DnaA [Escherichia coli O157:H7... gi\|187771794, gi... - gi\|187771794\|gb\|EDU35638.1\| chromosomal replication initiator protein DnaA [Escherichia coli O157:H7... gi\|168779924, gi... - gi\|189002469\|gb\|EDU71455.1\| chromosomal replication initiator protein DnaA [Escherichia coli O157:H7... gi\|168786532, gi... - gi\|189373439\|gb\|EDU91855.1\| chromosomal replication initiator protein DnaA [Escherichia coli O157:H7... gi\|188016856, gi... - gi\|188016856\|gb\|EDU54978.1\| chromosomal replication initiator protein DnaA [Escherichia coli O157:H7... gi\|168753591, gi... - gi\|189358966\|gb\|EDU77385.1\| chromosomal replication initiator protein DnaA [Escherichia coli O157:H7... gi\|254795705, gi... - gi\|254795705\|ref\|YP_003080542.1\| chromosomal replication initiator protein DnaA, DNA-binding transcr... DNAA_ECO57 - Chromosomal replication initiator protein DnaA OS=Escherichia coli O157:H7 GN=dnaA PE=3 SV=1	386.0	[0..1]	[467..1]
DNAA_SHIDS - Chromosomal replication initiator protein DnaA OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=...	386.0	[0..1]	[467..1]
DNAA_SHIBS - Chromosomal replication initiator protein DnaA OS=Shigella boydii serotype 4 (strain Sb227) GN=dnaA ...	385.0	[0..1]	[467..1]
tr\|A0A0G3HXH2\|A0... - Chromosomal replication initiator protein DnaA OS=Escherichia coli (strain K12) GN=dnaA PE=3 SV=2 gi\|227883923, gi... - gi\|227883923\|ref\|ZP_04001728.1\| chromosomal replication initiator protein DnaA, DNA-binding transcri... gi\|115515102, gi... - gi\|117625978\|ref\|YP_859301.1\| chromosomal replication initiation protein [Escherichia coli APEC O1],...	382.0	[0..2]	[467..6]
gi\|290550 - gi\|290550\|gb\|AAA62053.1\| dnaA (CG Site No. 851)	379.0	[0..2]	[467..6]
gi\|167401560, gi... - gi\|167401560\|ref\|ZP_02307054.1\| chromosomal replication initiator protein DnaA [Yersinia pestis biov... gi\|166958243, gi... - gi\|167422851\|ref\|ZP_02314604.1\| chromosomal replication initiator protein DnaA [Yersinia pestis biov... gi\|167055492, gi... - gi\|167425478\|ref\|ZP_02317231.1\| chromosomal replication initiator protein DnaA [Yersinia pestis biov... gi\|45438598, gi\|... - gi\|45443728\|ref\|NP_995267.1\| chromosomal replication initiation protein [Yersinia pestis biovar Micr... DNAA_YERPG - Chromosomal replication initiator protein DnaA OS=Yersinia pestis bv. Antiqua (strain Angola) GN=dna... gi\|165926099, gi... - gi\|165926099\|ref\|ZP_02221931.1\| chromosomal replication initiator protein DnaA [Yersinia pestis biov... gi\|218931074, gi... - gi\|218931074\|ref\|YP_002348949.1\| chromosomal replication initiation protein [Yersinia pestis CO92], ... gi\|166009506, gi... - gi\|166009506\|ref\|ZP_02230404.1\| chromosomal replication initiator protein DnaA [Yersinia pestis biov... DNAA_YERPS - Chromosomal replication initiator protein DnaA OS=Yersinia pseudotuberculosis serotype I (strain IP3... gi\|166205585, gi... - gi\|166213287\|ref\|ZP_02239322.1\| chromosomal replication initiator protein DnaA [Yersinia pestis biov... DNAA_YERP3 - Chromosomal replication initiator protein DnaA OS=Yersinia pseudotuberculosis serotype O:1b (strain ... gi\|149290376, gi... - gi\|150260968\|ref\|ZP_01917696.1\| chromosomal replication initiator protein [Yersinia pestis CA88-4125... DNAA_YERPP - Chromosomal replication initiator protein DnaA OS=Yersinia pestis (strain Pestoides F) GN=dnaA PE=3 ... gi\|229696170, gi... - gi\|229839804\|ref\|ZP_04459963.1\| chromosomal replication initiator protein DnaA, DNA-binding transcri... DNAA_YERPE - Chromosomal replication initiator protein DnaA OS=Yersinia pestis GN=dnaA PE=3 SV=1 gi\|229841889, gi... - gi\|229841889\|ref\|ZP_04462045.1\| chromosomal replication initiator protein DnaA, DNA-binding transcri... DNAA_YERPA - Chromosomal replication initiator protein DnaA OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=dn... DNAA_YERPN - Chromosomal replication initiator protein DnaA OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=d... gi\|229896766, gi... - gi\|229896766\|ref\|ZP_04511929.1\| chromosomal replication initiator protein DnaA, DNA-binding transcri... DNAA_YERPS - Chromosomal replication initiator protein DnaA OS=Yersinia pseudotuberculosis GN=dnaA PE=3 SV=1	379.0	[0..1]	[467..1]
gi\|153948 - gi\|153948\|gb\|AAA02815.1\| dnaA protein gi\|153948\|gb\|AAA... - dnaA protein	378.0	[0..1]	[467..1]
gi\|77958161 - gi\|77958161\|ref\|ZP_00822199.1\| COG0593: ATPase involved in DNA replication initiation [Yersinia berc...	378.0	[0..2]	[467..6]
DNAA_SALPA - Chromosomal replication initiator protein DnaA OS=Salmonella paratyphi A GN=dnaA PE=3 SV=1 DNAA_SALPA - Chromosomal replication initiator protein DnaA OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42)... gi\|238913091 - gi\|238913091\|ref\|ZP_04656928.1\| chromosomal replication initiation protein [Salmonella enterica subs... gi\|204928789, gi... - gi\|204928789\|ref\|ZP_03219988.1\| chromosomal replication initiator protein DnaA [Salmonella enterica ... DNAA_SALPB - Chromosomal replication initiator protein dnaA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB... DNAA_SALSV - Chromosomal replication initiator protein DnaA OS=Salmonella schwarzengrund (strain CVM19633) GN=dna... DNAA_SALTY - Chromosomal replication initiator protein dnaA OS=Salmonella typhimurium GN=dnaA PE=3 SV=2 DNAA_SALA4 - Chromosomal replication initiator protein DnaA OS=Salmonella agona (strain SL483) GN=dnaA PE=3 SV=1 DNAA_SALPK - Chromosomal replication initiator protein DnaA OS=Salmonella paratyphi A (strain AKU_12601) GN=dnaA ... DNAA_SALTY - Chromosomal replication initiator protein DnaA OS=Salmonella typhimurium (strain LT2 / SGSC1412 / AT... gi\|200388152, gi... - gi\|200388152\|ref\|ZP_03214764.1\| chromosomal replication initiator protein DnaA [Salmonella enterica ... DNAA_SALPB - Chromosomal replication initiator protein DnaA OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB... gi\|168818302, gi... - gi\|205344670\|gb\|EDZ31434.1\| chromosomal replication initiator protein DnaA [Salmonella enterica subs... DNAA_SALNS - Chromosomal replication initiator protein DnaA OS=Salmonella newport (strain SL254) GN=dnaA PE=3 SV=... DNAA_SALHS - Chromosomal replication initiator protein DnaA OS=Salmonella heidelberg (strain SL476) GN=dnaA PE=3 ... gi\|194470761, gi... - gi\|194470761\|ref\|ZP_03076745.1\| chromosomal replication initiator protein DnaA [Salmonella enterica ... lcl\|NC_016856.1_... - [gene=dnaA] [protein=chromosomal replication initiation protein] [protein_id=YP_005240105.1] [locati... gi\|205332569, gi... - gi\|205332569\|gb\|EDZ19333.1\| chromosomal replication initiator protein DnaA [Salmonella enterica subs... DNAA_SALTY - Chromosomal replication initiator protein DnaA OS=Salmonella typhimurium GN=dnaA PE=3 SV=2 gi\|168235478, gi... - gi\|197291232\|gb\|EDY30584.1\| chromosomal replication initiator protein DnaA [Salmonella enterica subs... gi\|168260377, gi... - gi\|205350503\|gb\|EDZ37134.1\| chromosomal replication initiator protein DnaA [Salmonella enterica subs... gi\|168464831, gi... - gi\|195632396\|gb\|EDX50880.1\| chromosomal replication initiator protein DnaA [Salmonella enterica subs... gi\|167548872, gi... - gi\|205325509\|gb\|EDZ13348.1\| chromosomal replication initiator protein DnaA [Salmonella enterica subs... gi\|167992432, gi... - gi\|205329368\|gb\|EDZ16132.1\| chromosomal replication initiator protein DnaA [Salmonella enterica subs...	378.0	[0..1]	[467..1]

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Predicted Domain #1

Region A:
Residues: [1-123]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSLWQQCL ARLQDELPAT EFSMWIRPLQ AELSDNTLAL YAPNRFVLDW VRDKYLNNIN  60
   61 GLLTSFCGAD APQLRFEVGT KPVTQTPQAA VTSNVAAPAQ VAQTQPQRAA PSTRSGWDNV 120
  121 PAP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.39794
Match:	2e0gA
Description:	No description for 2e0gA was found.

Predicted Domain #2

Region A:
Residues: [124-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEPTYRSNVN VKHTFDNFVE GKSNQLARAA ARQVADNPGG AYNPLFLYGG TGLGKTHLLH  60
   61 AVGNGIMARK PNAKVVYMHS ERFVQDMVKA LQNNAIEEFK RYYRSVDALL IDDIQFFANK 120
  121 ERSQEEFFHT FNALLEGNQQ IILTSDRYPK EINGVEDRLK SRFGWGLTVA IEPPELETRV 180
  181 AILMKKADEN DIRLPGEVAF FIAKRLRSNV RELEGALNRV IANANFTGRA ITIDFVREAL 240
  241 RDLLALQEKL VTIDNIQKTV AEYYKIKVAD LLSKRRSRSV ARPRQMAMAL AKELTNHSLP 300
  301 EIGDAFGGRD HTTVLHACRK IEQLREESHD IKEDFSNLIR TLSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.69897
Match:	2hcbA
Description:	No description for 2hcbA was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.37148167194523	bayes_pls_golite062009
binding	1.30574971150356	bayes_pls_golite062009
pyrophosphatase activity	1.16998111465319	bayes_pls_golite062009
nucleic acid binding	0.595576734443569	bayes_pls_golite062009
DNA binding	0.278289439071945	bayes_pls_golite062009
transcription regulator activity	0.272450877010668	bayes_pls_golite062009
helicase activity	0.00674361801283974	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: