YRC Public Data Repository - Protein Structure Prediction

Protein:	BTUC_ECOLI
Organism:	Escherichia coli
Length:	326 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BTUC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|76167036, gi\|... - gi\|76257950\|ref\|ZP_00765607.1\| transport system permease protein [Chloroflexus aurantiacus J-10-fl],...	240.0	[0..4]	[326..57]
gi\|68185993, gi\|... - gi\|91773082\|ref\|YP_565774.1\| ABC Fe3+-siderophore transporter, inner membrane subunit [Methanococcoi...	237.0	[0..5]	[326..31]
gi\|25296945 - pir\|\|AB2129 iron(III) dicitrate transport system permease protein all2585 [imported] - Nostoc sp. (s... gi\|17230077, gi\|... - gi\|17230077\|ref\|NP_486625.1\| iron(III) dicitrate transport system permease protein [Nostoc sp. PCC 7...	235.0	[0..3]	[326..12]
gi\|219992178, gi... - gi\|89211194\|ref\|ZP_01189569.1\| transport system permease protein [Halothermothrix orenii H 168], gi\|...	234.0	[0..6]	[325..1]
gi\|114845489, gi... - gi\|167039782\|ref\|YP_001662767.1\| transport system permease protein [Thermoanaerobacter sp. X514], gi... gi\|167037070, gi... - gi\|76796307\|ref\|ZP_00778672.1\| transport system permease protein [Thermoanaerobacter ethanolicus ATC... gi\|241884179, gi... - gi\|241903412\|ref\|ZP_04788136.1\| transport system permease protein [Thermoanaerobacter brockii subsp.... gi\|242230699, gi... - gi\|242257758\|ref\|ZP_04802610.1\| transport system permease protein [Thermoanaerobacter sp. X513], gi\|...	231.0	[0..5]	[326..13]
gi\|214034358, gi... - gi\|254479701\|ref\|ZP_05092994.1\| ABC transporter, FeCT family, permease protein [Carboxydibrachium pa... gi\|20808280 - gi\|20808280\|ref\|NP_623451.1\| ABC-type cobalamin/Fe3+-siderophores transport systems, permease compon... gi\|20516881, gi\|... - gi\|20808280\|ref\|NP_623451.1\| ABC-type cobalamin/Fe3+-siderophores transport systems, permease compon...	230.0	[0..5]	[326..13]
gi\|20089997, gi\|... - gi\|20089997\|ref\|NP_616072.1\| iron ABC transporter, permease protein [Methanosarcina acetivorans C2A]...	230.0	[0..11]	[326..15]
gi\|67987421, gi\|... - gi\|69285730\|ref\|ZP_00617069.1\| transport system permease protein [Kineococcus radiotolerans SRS30216...	230.0	[0..34]	[325..580]
gi\|45358745, gi\|... - gi\|45358745\|ref\|NP_988302.1\| transport system permease protein [Methanococcus maripaludis S2], gi\|45...	229.0	[0..5]	[326..8]
gi\|88601501, gi\|... - gi\|88601501\|ref\|YP_501679.1\| transport system permease protein [Methanospirillum hungatei JF-1], gi\|...	228.0	[0..2]	[326..19]

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Predicted Domain #1

Region A:
Residues: [1-326]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTLARQQQR QNIRWLLCLS VLMLLALLLS LCAGEQWISP GDWFTPRGEL FVWQIRLPRT  60
   61 LAVLLVGAAL AISGAVMQAL FENPLAEPGL LGVSNGAGVG LIAAVLLGQG QLPNWALGLC 120
  121 AIAGALIITL ILLRFARRHL STSRLLLAGV ALGIICSALM TWAIYFSTSV DLRQLMYWMM 180
  181 GGFGGVDWRQ SWLMLALIPV LLWICCQSRP MNMLALGEIS ARQLGLPLWF WRNVLVAATG 240
  241 WMVGVSVALA GAIGFIGLVI PHILRLCGLT DHRVLLPGCA LAGASALLLA DIVARLALAA 300
  301 AELPIGVVTA TLGAPVFIWL LLKAGR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.522879
Match:	1l7vA
Description:	ABC transporter involved in vitamin B12 uptake, BtuC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
iron ion transmembrane transporter activity	8.55593410962699	bayes_pls_golite062009
metal ion transmembrane transporter activity	7.151741771764	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	6.89351560294196	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	6.89303905792457	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	6.89303905792457	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	6.87925267157243	bayes_pls_golite062009
primary active transmembrane transporter activity	6.86902581504498	bayes_pls_golite062009
active transmembrane transporter activity	6.77850031149726	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	6.57608007042658	bayes_pls_golite062009
cation transmembrane transporter activity	6.31692387243447	bayes_pls_golite062009
ATPase activity, coupled	6.20998686742636	bayes_pls_golite062009
ion transmembrane transporter activity	6.20895469812824	bayes_pls_golite062009
ATPase activity	5.86694519684157	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	5.83345351962065	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	5.77899233548357	bayes_pls_golite062009
nucleoside-triphosphatase activity	5.53932239936879	bayes_pls_golite062009
heme transporter activity	5.52078940808773	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	5.48489417595047	bayes_pls_golite062009
pyrophosphatase activity	5.46424384705161	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	5.44387469717844	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	5.4435161646875	bayes_pls_golite062009
transporter activity	5.10647347588263	bayes_pls_golite062009
transmembrane transporter activity	4.86330633635492	bayes_pls_golite062009
substrate-specific transporter activity	3.90947011459529	bayes_pls_golite062009
hydrolase activity	3.81025268759093	bayes_pls_golite062009
vitamin transporter activity	3.49692616340822	bayes_pls_golite062009
cofactor transporter activity	3.1133731629348	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: