YRC Public Data Repository - Protein Structure Prediction

Protein:	BGLA_ECOLI
Organism:	Escherichia coli
Length:	479 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for BGLA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|26249317, gi\|... - gi\|26249317\|ref\|NP_755357.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli CFT073], gi\|26109725\|... gi\|237706454, gi... - gi\|237706454\|ref\|ZP_04536935.1\| 6-phospho-beta-glucosidase bglA [Escherichia sp. 3_2_53FAA], gi\|2268... gi\|91212280, gi\|... - gi\|91212280\|ref\|YP_542266.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli UTI89], gi\|91073854\|g...	520.0	[0..1]	[479..7]
gi\|190906511, gi... - gi\|75239245\|ref\|ZP_00723218.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida... gi\|115514256, gi... - gi\|117625132\|ref\|YP_854120.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli APEC O1], gi\|1155142... gi\|218366663, gi... - gi\|218559894\|ref\|YP_002392807.1\| 6-phospho-beta-glucosidase A [Escherichia coli S88], gi\|218366663\|e... gi\|227888451, gi... - gi\|227888451\|ref\|ZP_04006256.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli 83972], gi\|2278347...	520.0	[0..1]	[479..1]
gi\|208735249, gi... - gi\|208813972\|ref\|ZP_03255301.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC404... gi\|208808294, gi... - gi\|208808294\|ref\|ZP_03250631.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC420... gi\|195936520 - gi\|195936520\|ref\|ZP_03081902.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC402... gi\|189374222, gi... - gi\|189404802\|ref\|ZP_02810755.2\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC869... gi\|209760508, gi... - pir\|\|E91100 6-phospho-beta-glucosidase A [imported] - Escherichia coli (strain O157:H7, substrain R... gi\|217319639, gi... - gi\|217327272\|ref\|ZP_03443355.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. TW145... gi\|209399585, gi... - gi\|209399585\|ref\|YP_002272376.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC41... gi\|208741787, gi... - gi\|208821664\|ref\|ZP_03261984.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC404... gi\|189377630, gi... - gi\|189377630\|gb\|EDU96046.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC508], g... gi\|168775779, gi... - gi\|187768750\|gb\|EDU32594.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC4196], ... gi\|189369317, gi... - gi\|189369317\|gb\|EDU87733.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC4501], ... gi\|189402902, gi... - gi\|189402902\|ref\|ZP_02791902.2\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC448... gi\|189401917, gi... - gi\|189401917\|ref\|ZP_02778847.2\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC440... gi\|189009990, gi... - gi\|189009990\|ref\|ZP_02803922.2\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC407... gi\|188024609, gi... - gi\|188024609\|ref\|ZP_02772641.2\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC411... gi\|254594251, gi... - gi\|254794851\|ref\|YP_003079688.1\| 6-phospho-beta-glucosidase A [Escherichia coli O157:H7 str. TW14359... gi\|13363245, gi\|... - gi\|15833027\|ref\|NP_311800.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. Sakai], ... gi\|13363245, gi\|... - gi\|15833027\|ref\|NP_311800.1\| 6-phospho-beta-glucosidase A [Escherichia coli O157:H7], gi\|13363245\|db...	519.0	[0..1]	[479..1]
gi\|110344642, gi... - gi\|110643050\|ref\|YP_670780.1\| 6-phospho-beta-glucosidase BglA [Escherichia coli 536], gi\|110344642\|g...	519.0	[0..3]	[479..1]
gi\|887851 - gi\|887851\|gb\|AAA83082.1\| ORF_o479	518.0	[0..1]	[479..1]
gi\|157068041, gi... - gi\|75196853\|ref\|ZP_00706923.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida...	518.0	[0..1]	[479..1]
lcl\|NC_016856.1_... - [gene=bglA] [protein=6-phospho-beta-glucosidase] [protein_id=YP_005239187.1] [location=3228446..3229... gi\|199604335, gi... - gi\|200387237\|ref\|ZP_03213849.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enterica... gi\|207858314, gi... - gi\|207858314\|ref\|YP_002244965.1\| 6-phospho-beta-glucosidase [Salmonella enterica subsp. enterica ser... gi\|197243053, gi... - gi\|197264798\|ref\|ZP_03164872.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enterica... gi\|198243256, gi... - gi\|198243256\|ref\|YP_002217029.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enteric... gi\|194446388, gi... - gi\|194446388\|ref\|YP_002042303.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enteric... gi\|194450900, gi... - gi\|194450900\|ref\|YP_002047036.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enteric... gi\|168261786, gi... - gi\|205349280\|gb\|EDZ35911.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enterica ser... gi\|195633317, gi... - gi\|195633317\|gb\|EDX51731.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enterica ser... gi\|167994115, gi... - gi\|205328002\|gb\|EDZ14766.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enterica ser... gi\|168242839, gi... - gi\|205338227\|gb\|EDZ24991.1\| 6-phospho-beta-glucosidase BglA [Salmonella enterica subsp. enterica ser... gi\|16421602, gi\|... - gi\|16766352\|ref\|NP_461967.1\| 6-phospho-beta-glucosidase A [Salmonella typhimurium LT2], gi\|16421602\|...	517.0	[0..3]	[479..1]
gi\|197095403, gi... - gi\|197363926\|ref\|YP_002143563.1\| 6-phospho-beta-glucosidase [Salmonella enterica subsp. enterica ser... gi\|56129254, gi\|... - gi\|56414997\|ref\|YP_152072.1\| 6-phospho-beta-glucosidase [Salmonella enterica subsp. enterica serovar...	516.0	[0..3]	[479..1]
gi\|81246887, gi\|... - gi\|82545476\|ref\|YP_409423.1\| 6-phospho-beta-glucosidase A; cryptic [Shigella boydii Sb227], gi\|81246...	516.0	[0..1]	[479..1]
gi\|193070532, gi... - gi\|75234629\|ref\|ZP_00718960.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida... gi\|157077868, gi... - gi\|75187617\|ref\|ZP_00700884.1\| COG2723: Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosida... gi\|218555449, gi... - gi\|218555449\|ref\|YP_002388362.1\| 6-phospho-beta-glucosidase A [Escherichia coli IAI1], gi\|218362217\|...	516.0	[0..1]	[479..1]

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Predicted Domain #1

Region A:
Residues: [1-479]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVKKLTLPK DFLWGGAVAA HQVEGGWNKG GKGPSICDVL TGGAHGVPRE ITKEVLPGKY  60
   61 YPNHEAVDFY GHYKEDIKLF AEMGFKCFRT SIAWTRIFPK GDEAQPNEEG LKFYDDMFDE 120
  121 LLKYNIEPVI TLSHFEMPLH LVQQYGSWTN RKVVDFFVRF AEVVFERYKH KVKYWMTFNE 180
  181 INNQRNWRAP LFGYCCSGVV YTEHENPEET MYQVLHHQFV ASALAVKAAR RINPEMKVGC 240
  241 MLAMVPLYPY SCNPDDVMFA QESMRERYVF TDVQLRGYYP SYVLNEWERR GFNIKMEDGD 300
  301 LDVLREGTCD YLGFSYYMTN AVKAEGGTGD AISGFEGSVP NPYVKASDWG WQIDPVGLRY 360
  361 ALCELYERYQ RPLFIVENGF GAYDKVEEDG SINDDYRIDY LRAHIEEMKK AVTYDGVDLM 420
  421 GYTPWGCIDC VSFTTGQYSK RYGFIYVNKH DDGTGDMSRS RKKSFNWYKE VIASNGEKL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	123.0
Match:	1od0A
Description:	Beta-glucosidase A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity, hydrolyzing O-glycosyl compounds	4.55801959095491	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	4.29108420555514	bayes_pls_golite062009
hydrolase activity	2.98140830993539	bayes_pls_golite062009
glucosidase activity	1.92306554001182	bayes_pls_golite062009
catalytic activity	1.85569074294201	bayes_pls_golite062009
alpha-amylase activity	1.42264105957213	bayes_pls_golite062009
amylase activity	1.37652764526134	bayes_pls_golite062009
hexosaminidase activity	0.763360027922833	bayes_pls_golite062009
alpha-glucosidase activity	0.502835520523619	bayes_pls_golite062009
chitinase activity	0.500233744020165	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	0.266938437560648	bayes_pls_golite062009
beta-N-acetylhexosaminidase activity	0.263065978664289	bayes_pls_golite062009
binding	0.129334455670168	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: