YRC Public Data Repository - Protein Structure Prediction

Protein:	ARGK_ECOLI
Organism:	Escherichia coli
Length:	331 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARGK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|48765539 - ref\|ZP_00270089.1\| COG1703: Putative periplasmic protein kinase ArgK and related GTPases of G3E fami... gi\|83593813, gi\|... - gi\|83593813\|ref\|YP_427565.1\| arginine/ornithine transport system ATPase [Rhodospirillum rubrum ATCC ...	248.0	[0..7]	[325..8]
gi\|21927985 - gi\|21927985\|gb\|AAM77046.1\| putative GTPase/ATPase [Saccharopolyspora erythraea]	245.0	[0..1]	[328..1]
gi\|48836043 - ref\|ZP_00293040.1\| COG1703: Putative periplasmic protein kinase ArgK and related GTPases of G3E fami... gi\|71916894, gi\|... - gi\|72163162\|ref\|YP_290819.1\| arginine/ornithine transport system ATPase [Thermobifida fusca YX], gi\|...	245.0	[0..6]	[326..6]
gi\|90591838, gi\|... - gi\|90591838\|ref\|ZP_01247478.1\| ArgK protein [Flavobacterium johnsoniae UW101], gi\|90432317\|gb\|EAS576...	245.0	[0..4]	[329..38]
argK - argK LAO/AO transport system kinase 2058128:2059117 reverse MW:35000 gi\|192290426, gi... - gi\|192290426\|ref\|YP_001991031.1\| LAO/AO transport system ATPase [Rhodopseudomonas palustris TIE-1], ...	244.0	[0..6]	[325..9]
gi\|76638353, gi\|... - gi\|76638353\|ref\|XP_869341.1\| PREDICTED: similar to methylmalonic aciduria type A isoform 2 [Bos taur...	243.0	[0..4]	[330..85]
gi\|73978278 - gi\|73978278\|ref\|XP_539752.2\| PREDICTED: similar to methylmalonic aciduria type A [Canis familiaris]	243.0	[0..7]	[328..549]
gi\|78695644, gi\|... - gi\|78695644\|ref\|ZP_00860155.1\| ArgK protein [Bradyrhizobium sp. BTAi1], gi\|78516207\|gb\|EAP29507.1\| A...	242.0	[0..3]	[326..99]
gi\|77651672, gi\|... - gi\|91976399\|ref\|YP_569058.1\| arginine/ornithine transport system ATPase [Rhodopseudomonas palustris ...	241.0	[0..5]	[325..9]
gi\|114596301 - gi\|114596301\|ref\|XP_526697.2\| PREDICTED: methylmalonic aciduria type A [Pan troglodytes]	239.0	[0..7]	[327..86]

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Predicted Domain #1

Region A:
Residues: [1-331]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MINEATLAES IRRLRQGERA TLAQAMTLVE SRHPRHQALS TQLLDAIMPY CGNTLRLGVT  60
   61 GTPGAGKSTF LEAFGMLLIR EGLKVAVIAV DPSSPVTGGS ILGDKTRMND LARAEAAFIR 120
  121 PVPSSGHLGG ASQRARELML LCEAAGYDVV IVETVGVGQS ETEVARMVDC FISLQIAGGG 180
  181 DDLQGIKKGL MEVADLIVIN KDDGDNHTNV AIARHMYESA LHILRRKYDE WQPRVLTCSA 240
  241 LEKRGIDEIW HAIIDFKTAL TASGRLQQVR QQQSVEWLRK QTEEEVLNHL FANEDFDRYY 300
  301 RQTLLAVKNN TLSPRTGLRQ LSEFIQTQYF D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.0
Match:	2p67A
Description:	No description for 2p67A was found.

Predicted functions:

Term	Confidence	Notes
amino acid transmembrane transporter activity	2.01505980789636	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.95073642969863	bayes_pls_golite062009
pyrophosphatase activity	1.91141407779641	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.9017593265179	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.90014393273511	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	1.82370030183942	bayes_pls_golite062009
organic acid transmembrane transporter activity	1.79922369980544	bayes_pls_golite062009
transporter activity	1.55572428045529	bayes_pls_golite062009
ATPase activity	1.48474288797022	bayes_pls_golite062009
amine transmembrane transporter activity	1.46279910519982	bayes_pls_golite062009
transmembrane transporter activity	1.38483976298883	bayes_pls_golite062009
ATPase activity, coupled	1.37457738689583	bayes_pls_golite062009
active transmembrane transporter activity	1.24278046928678	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.2014318795788	bayes_pls_golite062009
primary active transmembrane transporter activity	1.19670408144267	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	1.17063957238561	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	1.16918853509059	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	1.16885789920943	bayes_pls_golite062009
hydrolase activity	1.09839981963412	bayes_pls_golite062009
binding	0.855534295206446	bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity	0.659246448488891	bayes_pls_golite062009
catalytic activity	0.605053499033488	bayes_pls_golite062009
purine ribonucleotide binding	0.5127850474754	bayes_pls_golite062009
ribonucleotide binding	0.51230334374838	bayes_pls_golite062009
purine nucleotide binding	0.50688037036449	bayes_pls_golite062009
nucleotide binding	0.49473184426584	bayes_pls_golite062009
amine-transporting ATPase activity	0.42499798704757	bayes_pls_golite062009
amino acid-transporting ATPase activity	0.40666423730781	bayes_pls_golite062009
substrate-specific transporter activity	0.0838665746103899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: