YRC Public Data Repository - Protein Structure Prediction

Protein:	ALN_ECOLI
Organism:	Escherichia coli
Length:	453 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALN_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|194423619, gi... - gi\|83587037\|ref\|ZP_00925667.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... gi\|251784018, gi... - gi\|251784018\|ref\|YP_002998322.1\| hypothetical protein B21_00467 [Escherichia coli BL21], gi\|24237629... gi\|253972481, gi... - gi\|254160580\|ref\|YP_003043688.1\| allantoinase [Escherichia coli B str. REL606], gi\|253972481\|gb\|ACT3... gi\|253325544, gi... - gi\|254287384\|ref\|YP_003053132.1\| allantoinase [Escherichia coli BL21(DE3)], gi\|253976691\|gb\|ACT42361...	346.0	[0..1]	[453..1]
gi\|188492046, gi... - gi\|75514630\|ref\|ZP_00736885.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... ALLB_ECOLC - Allantoinase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=allB PE=3 SV=1 gi\|124529321, gi... - gi\|124529321\|ref\|ZP_01700355.1\| Allantoinase [Escherichia coli B], gi\|124499921\|gb\|EAY47401.1\| Allan...	344.0	[0..1]	[453..1]
gi\|227884480, gi... - gi\|227884480\|ref\|ZP_04002285.1\| allantoinase [Escherichia coli 83972], gi\|227838566\|gb\|EEJ49032.1\| a... ALLB_ECOUT - Allantoinase OS=Escherichia coli (strain UTI89 / UPEC) GN=allB PE=3 SV=1 gi\|237707488, gi... - gi\|237707488\|ref\|ZP_04537969.1\| allantoinase [Escherichia sp. 3_2_53FAA], gi\|226898698\|gb\|EEH84957.1... ALLB_ECOL5 - Allantoinase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=allB PE=3 SV=1 ALLB_ECO45 - Allantoinase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=allB PE=3 SV=1 ALLB_ECOL6 - Allantoinase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=allB PE=3 SV=1 ALLB_ECOL6 - Allantoinase OS=Escherichia coli O6 GN=allB PE=3 SV=1 ALLB_ECO27 - Allantoinase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=allB PE=3 SV=1 gi\|190907387, gi... - gi\|75240705\|ref\|ZP_00724612.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... ALLB_ECO81 - Allantoinase OS=Escherichia coli O81 (strain ED1a) GN=allB PE=3 SV=1 sp\|B7UKI9\|ALLB_ECO27 - Allantoinase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=allB PE=3 SV=1 ALLB_ECOK1 - Allantoinase OS=Escherichia coli O1:K1 / APEC GN=allB PE=3 SV=1	344.0	[0..1]	[453..1]
gi\|192929171, gi... - gi\|75257848\|ref\|ZP_00729326.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... gi\|75238997, gi\|... - gi\|75238997\|ref\|ZP_00722979.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... gi\|190901848, gi... - gi\|75228714\|ref\|ZP_00715331.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... gi\|194429580, gi... - gi\|75209184\|ref\|ZP_00709435.1\| COG0044: Dihydroorotase and related cyclic amidohydrolases [Escherich... ALLB_ECO55 - Allantoinase OS=Escherichia coli (strain 55989 / EAEC) GN=allB PE=3 SV=1 ALLB_ECOSE - Allantoinase OS=Escherichia coli (strain SE11) GN=allB PE=3 SV=1 ALLB_ECO8A - Allantoinase OS=Escherichia coli O8 (strain IAI1) GN=allB PE=3 SV=1	343.0	[0..1]	[453..1]
gi\|52631436, gi\|... - gi\|62871419\|gb\|AAY18594.1\| dihydropyrimidinase [Bacillus sp. TS-23], gi\|52631436\|gb\|AAU85146.1\| dihy...	343.0	[0..3]	[451..1]
ALLB_ECOHS - Allantoinase OS=Escherichia coli O9:H4 (strain HS) GN=allB PE=3 SV=1	342.0	[0..1]	[453..1]
ALLB_SALCH - Allantoinase OS=Salmonella choleraesuis GN=allB PE=3 SV=1 ALLB_SALCH - Allantoinase OS=Salmonella choleraesuis (strain SC-B67) GN=allB PE=3 SV=1 ALLB_SALCH - Allantoinase OS=Salmonella choleraesuis GN=allB PE=3 SV=1	342.0	[0..1]	[453..1]
lcl\|NC_016856.1_... - [gene=allB] [protein=allantoinase] [protein_id=YP_005236226.1] [location=584652..586013] ALLB_SALPK - Allantoinase OS=Salmonella paratyphi A (strain AKU_12601) GN=allB PE=3 SV=1 ALLB_SALTY - Allantoinase OS=Salmonella typhimurium GN=allB PE=3 SV=1 ALLB_SALDC - Allantoinase OS=Salmonella dublin (strain CT_02021853) GN=allB PE=3 SV=1 gi\|199603198, gi... - gi\|200390753\|ref\|ZP_03217364.1\| allantoinase [Salmonella enterica subsp. enterica serovar Virchow st... ALLB_SALEP - Allantoinase OS=Salmonella enteritidis PT4 (strain P125109) GN=allB PE=3 SV=1 ALLB_SALHS - Allantoinase OS=Salmonella heidelberg (strain SL476) GN=allB PE=3 SV=1 gi\|194469356, gi... - gi\|194469356\|ref\|ZP_03075340.1\| allantoinase [Salmonella enterica subsp. enterica serovar Kentucky s... ALLB_SALA4 - Allantoinase OS=Salmonella agona (strain SL483) GN=allB PE=3 SV=1 gi\|197242580, gi... - gi\|197264325\|ref\|ZP_03164399.1\| allantoinase [Salmonella enterica subsp. enterica serovar Saintpaul ... gi\|168240357, gi... - gi\|205339917\|gb\|EDZ26681.1\| allantoinase [Salmonella enterica subsp. enterica serovar Heidelberg str... gi\|205350033, gi... - gi\|205350033\|gb\|EDZ36664.1\| allantoinase [Salmonella enterica subsp. enterica serovar Hadar str. RI_... gi\|205344127, gi... - gi\|205344127\|gb\|EDZ30891.1\| allantoinase [Salmonella enterica subsp. enterica serovar Weltevreden st... ALLB_SALNS - Allantoinase OS=Salmonella newport (strain SL254) GN=allB PE=3 SV=1 gi\|205324147, gi... - gi\|205324147\|gb\|EDZ11986.1\| allantoinase [Salmonella enterica subsp. enterica serovar Saintpaul str.... gi\|167990517, gi... - gi\|205330913\|gb\|EDZ17677.1\| allantoinase [Salmonella enterica subsp. enterica serovar 4,[5],12:i:- s... gi\|205333957, gi... - gi\|205333957\|gb\|EDZ20721.1\| allantoinase [Salmonella enterica subsp. enterica serovar Kentucky str. ... ALLB_SALTY - Allantoinase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=allB PE=3 SV=1 gi\|29138361, gi\|... - gi\|29142730\|ref\|NP_806072.1\| allantoinase [Salmonella enterica subsp. enterica serovar Typhi str. Ty... ALLB_SALTI - Allantoinase OS=Salmonella typhi GN=allB PE=3 SV=1 gi\|238911348 - gi\|238911348\|ref\|ZP_04655185.1\| allantoinase [Salmonella enterica subsp. enterica serovar Tennessee ... gi\|16759498 - gi\|16759498\|ref\|NP_455115.1\| allantoinase [Salmonella enterica subsp. enterica serovar Typhi str. CT... gi\|213160823 - gi\|213160823\|ref\|ZP_03346533.1\| allantoinase [Salmonella enterica subsp. enterica serovar Typhi str.... gi\|213427931 - gi\|213427931\|ref\|ZP_03360681.1\| allantoinase [Salmonella enterica subsp. enterica serovar Typhi str.... gi\|213855427 - gi\|213855427\|ref\|ZP_03383667.1\| allantoinase [Salmonella enterica subsp. enterica serovar Typhi str.... ALLB_SALPA - Allantoinase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=allB PE=3 SV=1 gi\|213999564 - gi\|213999564\|ref\|ZP_03410299.1\| allantoinase [Salmonella enterica subsp. enterica serovar Typhi str.... ALLB_SALTY - Allantoinase OS=Salmonella typhimurium GN=allB PE=3 SV=1 ALLB_SALTI - Allantoinase OS=Salmonella typhi GN=allB PE=3 SV=1 ALLB_SALPA - Allantoinase OS=Salmonella paratyphi A GN=allB PE=3 SV=1	342.0	[0..1]	[453..1]
ALLB_ECO24 - Allantoinase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=allB PE=3 SV=1	342.0	[0..1]	[453..1]
gi\|28211428, gi\|... - gi\|28211428\|ref\|NP_782372.1\| dihydropyrimidinase [Clostridium tetani E88], gi\|28203869\|gb\|AAO36309.1...	340.0	[0..3]	[450..4]

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Predicted Domain #1

Region A:
Residues: [1-453]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFDLIIKNG TVILENEARV VDIAVKGGKI AAIGQDLGDA KEVMDASGLV VSPGMVDAHT  60
   61 HISEPGRSHW EGYETGTRAA AKGGITTMIE MPLNQLPATV DRASIELKFD AAKGKLTIDA 120
  121 AQLGGLVSYN IDRLHELDEV GVVGFKCFVA TCGDRGIDND FRDVNDWQFF KGAQKLGELG 180
  181 QPVLVHCENA LICDELGEEA KREGRVTAHD YVASRPVFTE VEAIRRVLYL AKVAGCRLHV 240
  241 CHVSSPEGVE EVTRARQEGQ DVTCESCPHY FVLDTDQFEE IGTLAKCSPP IRDLENQKGM 300
  301 WEKLFNGEID CLVSDHSPCP PEMKAGNIMK AWGGIAGLQS CMDVMFDEAV QKRGMSLPMF 360
  361 GKLMATNAAD IFGLQQKGRI APGKDADFVF IQPNSSYVLT NDDLEYRHKV SPYVGRTIGA 420
  421 RITKTILRGD VIYDIEQGFP VAPKGQFILK HQQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.69897
Match:	1gkrA
Description:	L-hydantoinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uracil binding	2.6045173443981	bayes_pls_golite062009
pyrimidine binding	2.6045173443981	bayes_pls_golite062009
allantoinase activity	2.45571277189844	bayes_pls_golite062009
dihydroorotase activity	2.32070383330692	bayes_pls_golite062009
dihydropyrimidinase activity	2.27856136692645	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2.20489529944693	bayes_pls_golite062009
hydrolase activity	2.17584977880576	bayes_pls_golite062009
deaminase activity	1.79186203771221	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.60895003474033	bayes_pls_golite062009
adenine deaminase activity	1.4081199504179	bayes_pls_golite062009
thymine binding	1.34528530211689	bayes_pls_golite062009
AMP deaminase activity	0.8498975324894	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.573107361273483	bayes_pls_golite062009
binding	0.420164638111423	bayes_pls_golite062009
guanine deaminase activity	0.134430884998957	bayes_pls_golite062009
protein binding	0.0854348074331311	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: