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View Structure Prediction Details

Protein: sli-1
Organism: Caenorhabditis elegans
Length: 523 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sli-1.

Description E-value Query
Range
Subject
Range
gi|114588318 - gi|114588318|ref|XP_516635.2| PREDICTED: Cas-Br-M (murine) ecotropic retroviral transforming sequenc...
473.0 [0..35] [522..236]

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Predicted Domain #1
Region A:
Residues: [1-427]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSINTIFHR IHRFVNGTGN NARFVPSTNN STEALTLSPR AVPSTVSDRR FLLKACKFMD  60
   61 QVVKSCHSPR LNLKNSPPFI LDILPDTYTH LMLIFTQNND ILQDNDYLKI FLESMINKCK 120
  121 EIIKLFKTSA IYNDQSEERR KLTKMSLTFS HMLFEIKALF PEGIYIEDRF RMTKKEAESF 180
  181 WSHHFTKKNI VPWSTFFTAL EKHHGSTIGK MEAAELKATI DLSGDDFISN FEFDVFTRLF 240
  241 YPFKTLIKNW QTLTTAHPGY CAFLTYDEVK KRLEKLTKKP GSYIFRLSCT RPGQWAIGYV 300
  301 APDGKIYQTI PQNKSLIQAL HEGHKEGFYI YPNGRDQDIN LSKLMDVPQA DRVQVTSEQY 360
  361 ELYCEMGTTF ELCKICDDNE KNIKIEPCGH LLCAKCLANW QDSDGGGNTC PFCRYEIKGT 420
  421 NRVIIDR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 123.0
Match: 1fbvA
Description: Cbl; N-terminal domain of cbl (N-cbl); CBL
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.78762232945822 bayes_pls_golite062009
protein binding 1.4273874265634 bayes_pls_golite062009
signal transducer activity 1.37370552536239 bayes_pls_golite062009
molecular transducer activity 1.37370552536239 bayes_pls_golite062009
epidermal growth factor receptor binding 1.03934535504406 bayes_pls_golite062009
molecular adaptor activity 0.58947294551094 bayes_pls_golite062009
SH3/SH2 adaptor activity 0.52889761132084 bayes_pls_golite062009
calcium ion binding 0.292797014921594 bayes_pls_golite062009
insulin receptor binding 0.28737567192381 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.253080312769269 bayes_pls_golite062009
receptor binding 0.24683439420295 bayes_pls_golite062009
kinase activity 0.246780195377285 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.16106219404884 bayes_pls_golite062009
protein binding, bridging 0.0904972759345899 bayes_pls_golite062009
hydrolase activity 0.062117874431973 bayes_pls_golite062009
protein kinase activity 0.0337037979217971 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [428-523]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKPTPVEIEK AKNVAAAEKK LISLVPDVPP RTSSQTSSSY VNIKELENVE TSGEALAQVV  60
   61 NRQRAPSIQA PPLPPRLSAS EHQPHHPYTN TNSERE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle