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View Structure Prediction Details

Protein: CE36943
Organism: Caenorhabditis elegans
Length: 499 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE36943.

Description E-value Query
Range
Subject
Range
gi|220931774, gi... - gi|89211514|ref|ZP_01189876.1| Threonine dehydratase II [Halothermothrix orenii H 168], gi|89158891|...
401.0 [0..97] [497..1]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVAPSRKKSI IHHHDHSHES TPQKTHHHRV KQAERKRTAS ISKEDGMEYN KRVRKLHKAF  60
   61 LTHGAESPHV DDKQTSGSNS DTEAPLFDPD CDPENPK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [98-419]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLKFSDISSA AFNIKNGVQT TPCVRSLQLS SKCEMDLYFK KEYLQVTGSF KERGARYALS  60
   61 KMAEQFKKAG VIAASAGNHA LALSYHGQQM GIPVTVVMPV IAPLMKIQFC RSLGATVILK 120
  121 GESIAVAKDF ALRHAKENHL KYINGYDAID ILAGQGTIGL EILDQVPDVD TILVPVGGGG 180
  181 LIAGIATAVK TLKPDVHIYG IESETCPSFT EAYEAGHIIT SQAKASLADG LAVPTVGGNS 240
  241 LETAKGLVDK VITVKEESIA LSILRLLEVE KAVVEGGGAV GLAAILEGKV PELKGKKVVS 300
  301 ILSGGNIDTT VLGRSIERGL AV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 69.09691
Match: 1v71A
Description: Crystal Structure of S.pombe Serine Racemase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
threonine racemase activity 4.44340924206787 bayes_pls_golite062009
threonine synthase activity 3.59927532963055 bayes_pls_golite062009
cysteine synthase activity 3.57860549303214 bayes_pls_golite062009
L-threonine ammonia-lyase activity 3.33109959091277 bayes_pls_golite062009
catalytic activity 2.38994231321972 bayes_pls_golite062009
tryptophan synthase activity 1.99526226543975 bayes_pls_golite062009
lyase activity 1.87743897464083 bayes_pls_golite062009
carbon-oxygen lyase activity 0.923824749425553 bayes_pls_golite062009
binding 0.507026774040034 bayes_pls_golite062009
ammonia-lyase activity 0.476674617721478 bayes_pls_golite062009
carbon-nitrogen lyase activity 0.249761226675912 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [420-499]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DGRLVRLEVV VSDRPGGIAE LTTTIAHLGA SIKDIFHERA WISTDVFHVK VKVVAETRGK  60
   61 EHVEEIETAL KKIYDNVILH 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.69897
Match: 1tdjA
Description: THREONINE DEAMINASE (BIOSYNTHETIC) FROM E. COLI
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle