YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: hlh-14
Organism: Caenorhabditis elegans
Length: 246 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hlh-14.

Description E-value Query
Range
Subject
Range
gi|33355711 - gi|33355711|gb|AAQ16205.1| eukaryotic myogenic factor MYF-6 [Sus scrofa]
124.0 [0..2] [245..1]

Back

Predicted Domain #1
Region A:
Residues: [1-101]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLESLIVIF LNSHSCKIFQ ICTSSQSFDL ELFNSSLYNL VPIRFVPIST LLVPPIRLSR  60
   61 PAFPLTISLI HSVHPHSLLA TTVFPLSFYF PAQQKKEAMA K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [102-246]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNQVARNERE RKRVHQVNHG FDVLRNRLQP KNHTKKWSKA DTLREAVKYI QQLQVLLNQD  60
   61 PQQPSVSSST PDYTMNNSNN FNNYAVKEEF SMYLPQNYCP QNQMSVPHGD VSHNFNSPTS 120
  121 SVSSSSYSPT QMCYPPVSYS NYPHH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.221849
Match: 1r05A
Description: Solution Structure of Max B-HLH-LZ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.47866819971988 bayes_pls_golite062009
transcription regulator activity 2.04191582741352 bayes_pls_golite062009
DNA binding 1.881116513908 bayes_pls_golite062009
transcription factor activity 1.75305749487981 bayes_pls_golite062009
nucleic acid binding 1.70236865157557 bayes_pls_golite062009
protein binding 0.880820411513 bayes_pls_golite062009
transcription activator activity 0.314165294474 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle