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View Structure Prediction Details

Protein: gi|11357754, gi|...
Organism: Arabidopsis thaliana
Length: 406 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11357754, gi|....

Description E-value Query
Range
Subject
Range
SDN3_ARATH - Small RNA degrading nuclease 3 OS=Arabidopsis thaliana GN=SDN3 PE=1 SV=1
328.0 [0..1] [406..1]

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Predicted Domain #1
Region A:
Residues: [1-135]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELKLATAEK QVLDELVKLL QSRDLRGENG NWKEFLHVYD KNADSPSDPS RRSHEDLVQF  60
   61 LTTFKKKEDL QLLKCHANHL LIENLKQESQ DEDTPEQMLV RLTVEHPSYS LDYSFKPYSE 120
  121 DWFVSDVGMK MKKVM

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [136-303]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESTNMVAVDC EMVLCEDGTE GLVRVGVVDR DLKVILDEFV KPNKPVVDYR TDITGITAED  60
   61 IENASLSVVD IQETLQPFLS TGTILVGHSL NRDLEVLKID HPKVIDTALV FKYPNTRKLR 120
  121 RPSLNNLCKS ILGYEVRKTG VPHDCVHDAS AAMKLALAVV EKRVDTTI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 1wljA
Description: human ISG20
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 5.30591758406946 bayes_pls_golite062009
exoribonuclease activity 3.71639182685131 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 3.59362615133405 bayes_pls_golite062009
3'-5'-exoribonuclease activity 3.1992647486402 bayes_pls_golite062009
exonuclease activity 3.13676176369406 bayes_pls_golite062009
nuclease activity 3.11657409772275 bayes_pls_golite062009
ribonuclease H activity 2.91966688044755 bayes_pls_golite062009
single-stranded DNA specific 3'-5' exodeoxyribonuclease activity 2.75003136922541 bayes_pls_golite062009
endonuclease activity 2.63074055051349 bayes_pls_golite062009
endoribonuclease activity 2.59247838057313 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.57498413015114 bayes_pls_golite062009
hydrolase activity 2.41899414621161 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2.04408785855894 bayes_pls_golite062009
3'-5' exonuclease activity 1.44123900197846 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
nucleic acid binding 1.23371034593624 bayes_pls_golite062009
protein binding 1.16870279238939 bayes_pls_golite062009
deoxyribonuclease activity 1.1219517187744 bayes_pls_golite062009
transcription regulator activity 1.10433412699603 bayes_pls_golite062009
DNA binding 0.860359347662869 bayes_pls_golite062009
binding 0.762139256580538 bayes_pls_golite062009
DNA polymerase activity 0.717600245625866 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.708753843279937 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.598360955770972 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.568273228950698 bayes_pls_golite062009
0.49473250705373 bayes_pls_golite062009
transcription factor activity 0.332903382446869 bayes_pls_golite062009
exodeoxyribonuclease activity 0.278838342302102 bayes_pls_golite062009
exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.261428436029202 bayes_pls_golite062009
structure-specific DNA binding 0.0701825322473915 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.00214157813118243 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [304-406]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPSKEVEKAK LFLHKIPNNV PSEELEQVLS GKFTLDVKQA KTQGRYYCAF ALFHSSEDAD  60
   61 QAFEHIDGIE MTDSLGLPQK VVIIKLSSGS RASIYVRKMV QDE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.39
Match: 2cqpA
Description: Solution structure of the RNA binding domain of RNA-binding protein 12
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle