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View Structure Prediction Details

Protein: gi|9294249, gi|1...
Organism: Arabidopsis thaliana
Length: 690 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|9294249, gi|1....

Description E-value Query
Range
Subject
Range
gi|3819699 - gi|3819699|emb|CAA08758.1| BnMAP4K alpha2 [Brassica napus]
460.0 [0..1] [690..1]

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Predicted Domain #1
Region A:
Residues: [1-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDVAGLQEA AGARFSQIEL IGRGSFGDVY KAFDKDLNKE VAIKVIDLEE SEDEIEDIQK  60
   61 EISVLSQCRC PYITEYYGSY LHQTKLWIIM EYMAGGSVAD LLQSNNPLDE TSIACITRDL 120
  121 LHAVEYLHNE GKIHRDIKAA NILLSENGDV KVADFGVSAQ LTRTISRRKT FVGTPFWMAP 180
  181 EVIQNSEGYN EKADIWSLGI TVIEMAKGEP PLADLHPMRV LFIIPRETPP QLDEHFSRQV 240
  241 KEFVSLCLKK APAERPSAKE LIKHRFIKNA RKSPKLLERI RERPKYQVKE DEETPRNGAK 300
  301 APVESSGTV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.0
Match: 1u5qA
Description: Crystal Structure of the TAO2 Kinase Domain: Activation and Specifity of a Ste20p MAP3K
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphotransferase activity, alcohol group as acceptor 5.49988294224815 bayes_pls_golite062009
protein kinase activity 5.4586557943719 bayes_pls_golite062009
kinase activity 5.3287080791198 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.96052051118534 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
transferase activity 3.97138602499442 bayes_pls_golite062009
binding 2.15579529579992 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
protein binding 1.36269611679417 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.684204466593894 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.48345772948903 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.37115026509016 bayes_pls_golite062009
MAP kinase kinase activity 0.35402045013148 bayes_pls_golite062009
MAP kinase activity 0.26024936404169 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.196560862858137 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [310-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIARDERSQG APGYSFQGNT VKNAGWDFTV GGSQSIGTVR ALKPPQARER RQEVSPNRIS  60
   61 QRTTRPSGNQ WSSATGSTIS EASEGGFVRR HPFQNDHEDG FHEEDDSSLS GSGTVVIRTP 120
  121 RSSQSSSVFR EPSSGSSGRY AAFDDASASG TVVVRGQYDD SGSPRTPKSR LGIQERTSSA 180
  181 SEDSNANLAE AKAALDAGFR RGKARERLGM GNNNNDGKVN RRREQMADDS DYSRNSGDKS 240
  241 SKQKVVP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [557-690]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSEQVSDEED DSIWESLPAS LSVLLIPSLK EALGDDSKES TVRTVSRSLV MMEREKPGSC  60
   61 EAFVAKLIEL LGSSKEASVK ELHDMAVCVF AKTTPDNAEN KMKQANKEFS SNTNVSPLGR 120
  121 FLLSRWLGQS SRDL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.221849
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle