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View Structure Prediction Details

Protein: RBOHD_ARATH
Organism: Arabidopsis thaliana
Length: 921 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RBOHD_ARATH.

Description E-value Query
Range
Subject
Range
gi|3242789, gi|1... - gi|3242789|gb|AAC39479.1| respiratory burst oxidase protein D [Arabidopsis thaliana], pir||T51804 re...
791.0 [0..1] [921..1]

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Predicted Domain #1
Region A:
Residues: [1-158]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKMRRGNSSN DHELGILRGA NSDTNSDTES IASDRGAFSG PLGRPKRASK KNARFADDLP  60
   61 KRSNSVAGGR GDDDEYVEIT LDIRDDSVAV HSVQQAAGGG GHLEDPELAL LTKKTLESSL 120
  121 NNTTSLSFFR STSSRIKNAS RELRRVFSRR PSPAVRRF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.0
Match: 2cn5A
Description: No description for 2cn5A was found.

Predicted Domain #2
Region A:
Residues: [159-340]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRTSSAAIHA LKGLKFIATK TAAWPAVDQR FDKLSADSNG LLLSAKFWEC LGMNKESKDF  60
   61 ADQLFRALAR RNNVSGDAIT KEQLRIFWEQ ISDESFDAKL QVFFDMVDKD EDGRVTEEEV 120
  121 AEIISLSASA NKLSNIQKQA KEYAALIMEE LDPDNAGFIM IENLEMLLLQ APNQSVRMGD 180
  181 SR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.69897
Match: 2f2oA
Description: Structure of calmodulin bound to a calcineurin peptide: a new way of making an old binding mode
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [341-489]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ILSQMLSQKL RPAKESNPLV RWSEKIKYFI LDNWQRLWIM MLWLGICGGL FTYKFIQYKN  60
   61 KAAYGVMGYC VCVAKGGAET LKFNMALILL PVCRNTITWL RNKTKLGTVV PFDDSLNFHK 120
  121 VIASGIVVGV LLHAGAHLTC DFPRLIAAD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [490-921]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDTYEPMEKY FGDQPTSYWW FVKGVEGWTG IVMVVLMAIA FTLATPWFRR NKLNLPNFLK  60
   61 KLTGFNAFWY THHLFIIVYA LLIVHGIKLY LTKIWYQKTT WMYLAVPILL YASERLLRAF 120
  121 RSSIKPVKMI KVAVYPGNVL SLHMTKPQGF KYKSGQFMLV NCRAVSPFEW HPFSITSAPG 180
  181 DDYLSVHIRT LGDWTRKLRT VFSEVCKPPT AGKSGLLRAD GGDGNLPFPK VLIDGPYGAP 240
  241 AQDYKKYDVV LLVGLGIGAT PMISILKDII NNMKGPDRDS DIENNNSNNN SKGFKTRKAY 300
  301 FYWVTREQGS FEWFKGIMDE ISELDEEGII ELHNYCTSVY EEGDARVALI AMLQSLQHAK 360
  361 NGVDVVSGTR VKSHFAKPNW RQVYKKIAVQ HPGKRIGVFY CGMPGMIKEL KNLALDFSRK 420
  421 TTTKFDFHKE NF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.69897
Match: 1cqxA
Description: Flavohemoglobin, N-terminal domain; Flavohemoglobin, central domain; Flavohemoglobin, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 3.63104057348215 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 3.51215695612257 bayes_pls_golite062009
NADH dehydrogenase (ubiquinone) activity 3.16088106136981 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, heme protein as acceptor 3.111558299994 bayes_pls_golite062009
oxygen binding 3.00647431286466 bayes_pls_golite062009
riboflavin synthase activity 2.93302227890511 bayes_pls_golite062009
transporter activity 2.82854186201092 bayes_pls_golite062009
substrate-specific transporter activity 2.74894673967321 bayes_pls_golite062009
NADH dehydrogenase activity 2.39225626523677 bayes_pls_golite062009
NADH dehydrogenase (quinone) activity 2.34041929019601 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor 2.2317814267351 bayes_pls_golite062009
FAD binding 2.07600122867642 bayes_pls_golite062009
oxygen transporter activity 1.78021144232114 bayes_pls_golite062009
coenzyme binding 1.66552102285114 bayes_pls_golite062009
molecular transducer activity 1.59457655213395 bayes_pls_golite062009
signal transducer activity 1.59457655213395 bayes_pls_golite062009
cytochrome-b5 reductase activity 1.5685421124725 bayes_pls_golite062009
cofactor binding 1.53717310937468 bayes_pls_golite062009
catalytic activity 1.45374095556065 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor 1.39469367242077 bayes_pls_golite062009
binding 1.33256635332573 bayes_pls_golite062009
protein binding 1.29518074303313 bayes_pls_golite062009
NADP or NADPH binding 1.18833847639357 bayes_pls_golite062009
receptor activity 0.977817619616883 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 0.90349352746963 bayes_pls_golite062009
FMN binding 0.649158247260553 bayes_pls_golite062009
antioxidant activity 0.46048982927229 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 0.431171115433616 bayes_pls_golite062009
peroxidase activity 0.431171115433616 bayes_pls_golite062009
NAD(P)H oxidase activity 0.270721094503631 bayes_pls_golite062009
transferase activity 0.00498326987177106 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle