| Protein: | SIR1_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 473 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIR1_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
414.0 | [0..1] | [473..1] |
|
Region A: Residues: [1-267] |
1 11 21 31 41 51
| | | | | |
1 MSLGYAEKLS FIEDVGQVGM AEFFDPSHLL QCKIEELAKL IQKSKHLVVF TGAGISTSCG 60
61 IPDFRGPKGI WTLQREGKDL PKASLPFHRA MPSMTHMALV ELERAGILKF VISQNVDGLH 120
121 LRSGIPREKL SELHGDSFME MCPSCGAEYL RDFEVETIGL KETSRKCSVE KCGAKLKDTV 180
181 LDWEDALPPK EIDPAEKHCK KADLVLCLGT SLQITPACNL PLKCLKGGGK IVIVNLQKTP 240
241 KDKKANVVIH GLVDKVVAGV MESLNMK
|
| Detection Method: |  |
| Confidence: | 67.69897 |
| Match: | 1m2gA |
| Description: | AF1676, Sir2 homolog (Sir2-AF1?) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein deacetylase activity | 9.15022242957651 | bayes_pls_golite062009 |
| histone deacetylase activity | 9.04876491350231 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 8.13038616303736 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity | 8.13038616303736 | bayes_pls_golite062009 |
| deacetylase activity | 8.11496387956068 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K14 specific) | 6.02509672218091 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 5.83127897351395 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity (H3-K9 specific) | 4.76068488405318 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity (H3-K14 specific) | 4.76068488405318 | bayes_pls_golite062009 |
| histone deacetylase activity (H3-K9 specific) | 3.4896257195243 | bayes_pls_golite062009 |
| NAD-dependent histone deacetylase activity (H4-K16 specific) | 3.45714518480692 | bayes_pls_golite062009 |
| transcription regulator activity | 2.9155913558118 | bayes_pls_golite062009 |
| DNA binding | 2.43141001866996 | bayes_pls_golite062009 |
| nucleic acid binding | 2.41433477472968 | bayes_pls_golite062009 |
| transcription repressor activity | 2.24657784428979 | bayes_pls_golite062009 |
| binding | 2.06552694538163 | bayes_pls_golite062009 |
| histone binding | 1.71445510915336 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.64212790017753 | bayes_pls_golite062009 |
| nucleosome binding | 1.5125174755597 | bayes_pls_golite062009 |
| transcription factor activity | 1.30143289828088 | bayes_pls_golite062009 |
| transporter activity | 1.23939100911116 | bayes_pls_golite062009 |
| transcription factor binding | 1.14766678956419 | bayes_pls_golite062009 |
| tubulin deacetylase activity | 1.11434618720209 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.07379627981357 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.961690831509865 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.82062598660259 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.7975957649836 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.77616501068364 | bayes_pls_golite062009 |
| catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.5949973363213 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.57969598853155 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.54005617175343 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.53162622210835 | bayes_pls_golite062009 |
| transferase activity | 0.483523935618287 | bayes_pls_golite062009 |
| protein binding | 0.475479132768057 | bayes_pls_golite062009 |
| hydrolase activity | 0.454589093015975 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | 0.114062221123972 | bayes_pls_golite062009 |
| NAD+ ADP-ribosyltransferase activity | 0.0099486881187274 | bayes_pls_golite062009 |
|
Region A: Residues: [268-473] |
1 11 21 31 41 51
| | | | | |
1 IPPYVRIDLF QIILTQSISG DQRFINWTLR VASVHGLTSQ LPFIKSIEVS FSDNHNYKDA 60
61 VLDKQPFLMK RRTARNETFD IFFKVNYSDG CDCVSTQLSL PFEFKISTEE HVEIIDKEAV 120
121 LQSLREKAVE ESSCGQSGVV ERRVVSEPRS EAVVYATVTS LRTYHSQQSL LANGDLKWKL 180
181 EGSGTSRKRS RTGKRKSKAL AEETKA
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
