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View Structure Prediction Details

Protein: MNS5_ARATH
Organism: Arabidopsis thaliana
Length: 574 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNS5_ARATH.

Description E-value Query
Range
Subject
Range
gi|92893614 - gi|92893614|gb|ABE91840.1| Glycoside hydrolase, family 47 [Medicago truncatula]
680.0 [0..7] [571..3]

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Predicted Domain #1
Region A:
Residues: [1-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCPIHPRRL FLCLLISLTF FVVDPSSQHI EVKKKQMREK VREMFYHAYD NYMTYAFPHD  60
   61 ELKPLTKSFT DSLSELGNLK LEHLPTDYNG SAVTLVESLS SLAILGNSTE FEKGVLWLSE 120
  121 NLTFDIDARV NLFECNIRVL GGLISAHLLA IDPNNRLIQG SYNNQLLRLA EDLGKRFLPA 180
  181 FETPTGLPYA WINLKNGVME NETTETSTSG CGSLVLEMGA LSRLTGDPRF ESAALRALRQ 240
  241 LWRMRSSLDL LGTTLDVVTG EWIEYSSSIG AGVDSFYEYL LKAYILFGKE DYWRMFHSAY 300
  301 LASQKYFRHG PWYHEANMWS GKPTYWQLTS LQAFWPGLQV LVGDIAAANS SHREFFHVWE 360
  361 KFGVLPERYL LDHQIIHPTM KYYPLRPELA ESTFYLYQAT KDPWYLDVGE SMVKSLNLYT 420
  421 KVPGGFASVR DVTTMQLEDH QHSFFLAETC KYLYLLFDDS FVAKRNYIFT TEGHPIQVVS 480
  481 S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 152.0
Match: 1nxcA
Description: Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyl-oligosaccharide mannosidase activity 7.089685350864 bayes_pls_golite062009
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 6.95179264736435 bayes_pls_golite062009
mannosidase activity 5.20286438265852 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.31319275372149 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.65589746311782 bayes_pls_golite062009
binding 1.49199031708525 bayes_pls_golite062009
catalytic activity 1.31873306707813 bayes_pls_golite062009
cation binding 0.362242764130218 bayes_pls_golite062009
metal ion binding 0.362242764130218 bayes_pls_golite062009
protein binding 0.36081692928767 bayes_pls_golite062009
ion binding 0.355220167272296 bayes_pls_golite062009
calcium ion binding 0.121126738064555 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [482-574]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WHEKLPETYF SGNWTLSKSG AWESRASALS LQVCPLISLN SRHPEQQRES ACHVLDEQIN  60
   61 HKCWSNKECG VDATTCRLRT CSGVGYCGLW NPL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.99
Match: 2c4bA
Description: Inhibitor cystine knot protein McoEeTI fused to the catalytically inactive barnase mutant H102A
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle