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View Structure Prediction Details

Protein: UNG_ARATH
Organism: Arabidopsis thaliana
Length: 330 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UNG_ARATH.

Description E-value Query
Range
Subject
Range
UNG_MOUSE - Uracil-DNA glycosylase OS=Mus musculus GN=Ung PE=2 SV=2
425.0 [0..7] [329..5]

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Predicted Domain #1
Region A:
Residues: [1-95]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSTPKTLM DFFQPAKRLK ASPSSSSFPA VSVAGGSRDL GSVANSPPRV TVTTSVADDS  60
   61 SGLTPEQIAR AEFNKFVAKS KRNLAVCSER VTKAK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [96-330]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEGNCYVPLS ELLVEESWLK ALPGEFHKPY AKSLSDFLER EIITDSKSPL IYPPQHLIFN  60
   61 ALNTTPFDRV KTVIIGQDPY HGPGQAMGLS FSVPEGEKLP SSLLNIFKEL HKDVGCSIPR 120
  121 HGNLQKWAVQ GVLLLNAVLT VRSKQPNSHA KKGWEQFTDA VIQSISQQKE GVVFLLWGRY 180
  181 AQEKSKLIDA TKHHILTAAH PSGLSANRGF FDCRHFSRAN QLLEEMGIPP IDWQL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 108.0
Match: 1eugA
Description: Uracil-DNA glycosylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA N-glycosylase activity 5.22461096584694 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 4.68115068202636 bayes_pls_golite062009
uracil DNA N-glycosylase activity 4.48822773983461 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 2.66280504021689 bayes_pls_golite062009
single-strand selective uracil DNA N-glycosylase activity 2.14678866447561 bayes_pls_golite062009
hydrolase activity 1.91716804176625 bayes_pls_golite062009
catalytic activity 1.59111295908728 bayes_pls_golite062009
mismatch base pair DNA N-glycosylase activity 1.34999321643757 bayes_pls_golite062009
binding 1.2276262882727 bayes_pls_golite062009
structure-specific DNA binding 1.22310035950527 bayes_pls_golite062009
nucleic acid binding 0.901890891144085 bayes_pls_golite062009
DNA binding 0.850361767185031 bayes_pls_golite062009
transcription regulator activity 0.543168797464517 bayes_pls_golite062009
single-stranded DNA binding 0.48698673207018 bayes_pls_golite062009
protein binding 0.272261244770552 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle