Protein: | cash-1 |
Organism: | Caenorhabditis elegans |
Length: | 678 amino acids |
Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for cash-1.
Description | E-value | Query Range |
Subject Range |
|
479.0 | [0..34] | [677..1032] |
Region A: Residues: [1-159] |
1 11 21 31 41 51 | | | | | | 1 MEDASQLSNS QNDKAKDETT RPQYTMSGIL HFIQHEWTKN ELDRTRWEAE RAEMQARIAF 60 61 LQGERKGQEN LKQDLVRRIK MLEFCLKQER AKNYRLTHNG EEPPSLEESP NENSAPSENS 120 121 HLTADLDAYI NDAGEAGGSF RQGRLLLKRY LEEIGYSEH |
Detection Method: | |
Confidence: | 11.522879 |
Match: | 2i1jA |
Description: | No description for 2i1jA was found. |
Region A: Residues: [160-300] |
1 11 21 31 41 51 | | | | | | 1 IMDVRSFRVK NLLGLLPQAD LPSSERLNGR KEKSDSDSDD GHDDAALDAD ASKAFEEFDF 60 61 LNNMDAKEKG SDDDWAGKGA SFEKLIKQYK DDPKVKRRSR TSTEESEEKT SNDVQKNLET 120 121 DVPPGIRSAI DAAAQEELPV R |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
Region A: Residues: [301-678] |
1 11 21 31 41 51 | | | | | | 1 RQGRRSANFG YGNGNELDVA LGMQDNDNMD IKDEFKDEDD DPNAQQVKWN IKVTLRSHLD 60 61 SIRAMQFHPV EPVLFTASED GLIKLWNLDQ KKDEKHNSGG TELEPVYTFR GHKGPVLCLV 120 121 LSPTGDHLYT GGIDGNICCF NVPSSNGDPF DSYDPRVLTE TLTGHTDAIW SVAYHSSNSR 180 181 LVSASSDSTV RLWEPGNGEP LIRTIGAPKS GILPTSVDFV STETSHLLAA YTNCYAQIID 240 241 IDTGSTVMVF DFGAVTGSPT MNKIVSHPTM PLTLIGGEDR TIRYFDNTNG SIIHEAIAHV 300 301 EGVSSLAIDP NGLYLLSGSH DGSIRMWNME KRSCLQEISA HRKKNDSAVT SVAFHPSRSL 360 361 IGSAGADSLA KVYVSGSN |
Detection Method: | |
Confidence: | 72.69897 |
Match: | 1vyhC |
Description: | PAF-AH Holoenzyme: Lis1/Alfa2 |
Matching Structure (courtesy of the PDB): |
Term | Confidence | Notes |
6.67009948605948 | bayes_pls_golite062009 | |
histone methyltransferase activity (H3-K4 specific) | 4.71992275913384 | bayes_pls_golite062009 |
GTPase activity | 4.02994814377904 | bayes_pls_golite062009 |
RNA binding | 3.77273677738815 | bayes_pls_golite062009 |
actin binding | 3.31804728298431 | bayes_pls_golite062009 |
S-adenosylmethionine-dependent methyltransferase activity | 3.25521258308263 | bayes_pls_golite062009 |
cytoskeletal protein binding | 3.1056443224755 | bayes_pls_golite062009 |
tubulin binding | 2.76945430061825 | bayes_pls_golite062009 |
microtubule binding | 2.72684103222924 | bayes_pls_golite062009 |
dynein binding | 2.54821997913979 | bayes_pls_golite062009 |
binding | 2.42570478946173 | bayes_pls_golite062009 |
transcription regulator activity | 2.3610959773142 | bayes_pls_golite062009 |
nucleic acid binding | 2.30918780727915 | bayes_pls_golite062009 |
snoRNA binding | 2.27164613239345 | bayes_pls_golite062009 |
transcription repressor activity | 2.14857757853663 | bayes_pls_golite062009 |
dynactin binding | 1.92897254169098 | bayes_pls_golite062009 |
histone methyltransferase activity | 1.85632145559025 | bayes_pls_golite062009 |
DNA binding | 1.71685536470455 | bayes_pls_golite062009 |
actin filament binding | 1.5197243426595 | bayes_pls_golite062009 |
structural molecule activity | 1.47097979074281 | bayes_pls_golite062009 |
protein methyltransferase activity | 1.35170368882651 | bayes_pls_golite062009 |
transcription corepressor activity | 1.32093016237625 | bayes_pls_golite062009 |
protein binding | 1.21879977456466 | bayes_pls_golite062009 |
transporter activity | 1.21549336905926 | bayes_pls_golite062009 |
general RNA polymerase II transcription factor activity | 1.21305848427711 | bayes_pls_golite062009 |
lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
protein-lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
histone-lysine N-methyltransferase activity | 1.15313682561559 | bayes_pls_golite062009 |
receptor activity | 1.12819778129653 | bayes_pls_golite062009 |
G-protein-coupled receptor binding | 1.11754260203517 | bayes_pls_golite062009 |
transcription factor activity | 1.08768505897883 | bayes_pls_golite062009 |
mRNA binding | 1.05053985350578 | bayes_pls_golite062009 |
microtubule plus-end binding | 1.01166033978052 | bayes_pls_golite062009 |
molecular transducer activity | 0.974380908248463 | bayes_pls_golite062009 |
signal transducer activity | 0.974380908248463 | bayes_pls_golite062009 |
angiotensin receptor binding | 0.920323565472959 | bayes_pls_golite062009 |
type 1 angiotensin receptor binding | 0.920323565472959 | bayes_pls_golite062009 |
substrate-specific transporter activity | 0.734793983890004 | bayes_pls_golite062009 |
histone binding | 0.685319917508843 | bayes_pls_golite062009 |
RNA polymerase II transcription factor activity | 0.676924760416604 | bayes_pls_golite062009 |
transcription factor binding | 0.489473003915035 | bayes_pls_golite062009 |
dynein intermediate chain binding | 0.443846546939402 | bayes_pls_golite062009 |
receptor binding | 0.316169754698691 | bayes_pls_golite062009 |
transcription cofactor activity | 0.30761651528651 | bayes_pls_golite062009 |
protein kinase activity | 0.229242350006544 | bayes_pls_golite062009 |
enzyme regulator activity | 0.161639372576406 | bayes_pls_golite062009 |
chromatin binding | 0.151977098745772 | bayes_pls_golite062009 |
structural constituent of cytoskeleton | 0.118975415284669 | bayes_pls_golite062009 |
nucleoside-triphosphatase activity | 0.00585398682921312 | bayes_pls_golite062009 |
N-methyltransferase activity | 0.00335766408304172 | bayes_pls_golite062009 |