| Protein: | sir-2.2 |
| Organism: | Caenorhabditis elegans |
| Length: | 289 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sir-2.2.
| Description | E-value | Query Range |
Subject Range |
|
|
302.0 | [0..5] | [289..33] |
|
Region A: Residues: [1-289] |
1 11 21 31 41 51
| | | | | |
1 MAQKFVPEAA ELCENSLKKF ISLIGTVDKL LVISGAGIST ESVPGIPDYR SKDVGLYARI 60
61 AHKPIYFQDY MRSNRCRQRY WSRNFLAWPR FGQAAPNINH YALSKWEASD RFQWLITQNV 120
121 DGLHLKAGSK MVTELHGSAL QVKCTTCDYI ESRQTYQDRL DYANPGFKEE HVAPGELAPD 180
181 GDIILPLGTE KGFQIPECPS CGGLMKTDVT FFGENVNMDK VNFCYEKVNE CDGILSLGTS 240
241 LAVLSGFRFI HHANMKKKPI FIVNIGPTRA DHMATMKLDY KISDVLKEM
|
| Detection Method: |  |
| Confidence: | 70.154902 |
| Match: | 1ma3A |
| Description: | AF0112, Sir2 homolog (Sir2-AF2) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| NAD-dependent histone deacetylase activity | 4.66387831647923 | bayes_pls_golite062009 |
| NAD-dependent protein deacetylase activity | 4.66387831647923 | bayes_pls_golite062009 |
| NAD+ ADP-ribosyltransferase activity | 4.62921662347995 | bayes_pls_golite062009 |
| histone deacetylase activity | 4.52265070993834 | bayes_pls_golite062009 |
| protein deacetylase activity | 4.51418609991523 | bayes_pls_golite062009 |
| deacetylase activity | 3.60611826633675 | bayes_pls_golite062009 |
| transcription regulator activity | 2.31731368009317 | bayes_pls_golite062009 |
| DNA binding | 1.84059392605809 | bayes_pls_golite062009 |
| nucleic acid binding | 1.83132687449755 | bayes_pls_golite062009 |
| transcription repressor activity | 1.74876325396581 | bayes_pls_golite062009 |
| binding | 1.63619372613603 | bayes_pls_golite062009 |
| hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | 1.38412624618353 | bayes_pls_golite062009 |
| transcription corepressor activity | 1.16656035070431 | bayes_pls_golite062009 |
| transporter activity | 1.02987325768951 | bayes_pls_golite062009 |
| NAD(P)+-protein-arginine ADP-ribosyltransferase activity | 0.963519974868694 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.879539673228343 | bayes_pls_golite062009 |
| transcription factor activity | 0.758967814548108 | bayes_pls_golite062009 |
| catalytic activity | 0.739210399081789 | bayes_pls_golite062009 |
| transcription factor binding | 0.64778523540991 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.62029498163975 | bayes_pls_golite062009 |
| histone binding | 0.60825982588532 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.56000396203236 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.52020182886741 | bayes_pls_golite062009 |
| protein binding | 0.475479132768057 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.47231237137431 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.128843577740998 | bayes_pls_golite062009 |
| hydrolase activity | 0.0875567934348688 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.05634462944063 | bayes_pls_golite062009 |
