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View Structure Prediction Details

Protein: ent-1
Organism: Caenorhabditis elegans
Length: 445 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ent-1.

Description E-value Query
Range
Subject
Range
gi|114607582 - gi|114607582|ref|XP_518505.2| PREDICTED: solute carrier family 29 (nucleoside transporters), member ...
301.0 [0..4] [443..242]

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Predicted Domain #1
Region A:
Residues: [1-445]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAVELQPL NKTKKVEEES PEPEDKGNLV FYIILLHGIG TLMPWNMLIT ISYDYFESYK  60
   61 MLANSTIDMD TGVVTGYPTV YSSNFQSFQT IASQVPNLLL NLLNIFIVVK GGLASRITVG 120
  121 LSIVAVCVIT TMMFIYVETS TWLTGFFTLT IITIIVLNGA NGVYQNSIFG LASELPFKYT 180
  181 NAVIIGNNLC GTFVTLLSMS TKAVTRNILD RSFAYFSIAL ITLVFCFISF HILKKQRFYQ 240
  241 YYSTRAERQR NKNDEAVDSE GKVANYIATF KEAFPQLINV FLVFFVTLSI FPGVMMYVKD 300
  301 EKKGGVYDFP LPQKYFMDVT TFLQFNVFAF IGSIVAGRKQ WPAPNKLWIP VYLRLLYIPF 360
  361 FIFCNYLPET RSLPVFFEST WLFVIIAASM SFGSGYFSGL AMMYTSKTVD PSKAQVAGMM 420
  421 AGFFLISGIV SGLIFTMVIK MVVTA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transporter activity 4.09176719149278 bayes_pls_golite062009
substrate-specific transporter activity 3.59744164024479 bayes_pls_golite062009
transmembrane transporter activity 3.5865018981083 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 3.54194478414824 bayes_pls_golite062009
ion transmembrane transporter activity 2.21266150105753 bayes_pls_golite062009
cation transmembrane transporter activity 1.79369588808394 bayes_pls_golite062009
active transmembrane transporter activity 1.59419818573076 bayes_pls_golite062009
binding 1.45862166005114 bayes_pls_golite062009
secondary active transmembrane transporter activity 1.22264637452409 bayes_pls_golite062009
polyol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
alcohol transmembrane transporter activity 0.924836669821548 bayes_pls_golite062009
glycerol transmembrane transporter activity 0.812001619402678 bayes_pls_golite062009
symporter activity 0.74591237387473 bayes_pls_golite062009
solute:cation symporter activity 0.74591237387473 bayes_pls_golite062009
sugar:hydrogen symporter activity 0.143419068761182 bayes_pls_golite062009
cation:sugar symporter activity 0.143419068761182 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle