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View Structure Prediction Details

Protein: syn-1
Organism: Caenorhabditis elegans
Length: 306 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for syn-1.

Description E-value Query
Range
Subject
Range
gi|109099266 - gi|109099266|ref|XP_001111568.1| PREDICTED: similar to syntaxin 2 isoform 2 [Macaca mulatta]
206.0 [0..51] [299..131]

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Predicted Domain #1
Region A:
Residues: [1-306]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRDRLKELQ EKATVNTIHA YNYDPPARKY DVESQPLINQ DADFEMFLER CSNIRGGLKS  60
   61 LEEDYDAVVQ LHGALLSTPG ADSENSNKLK SHNQMFFSKA EQIKNSLKIL SEETSRIPTT 120
  121 ACGIMRAKSD QVKSIYKTFE NIMLNFNREQ DEYKEKAKRK IVDYLKIRNM QLSDEEIENA 180
  181 VSSGNLSEVT KGVMLALNEK KALYDEVKSR ADELKNLERQ MGELAQMFHD LHIMVVSQGE 240
  241 MVDSIVNSVE NATEYAKQAR GNVEEARNLQ KRARKMKVCI IIGSIIAVLI LILFIQSAVC 300
  301 HFTPIC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.69897
Match: 1dn1B
Description: Syntaxin 1A N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphatidic acid binding 8.51970136264329 bayes_pls_golite062009
SNAP receptor activity 3.50393203740159 bayes_pls_golite062009
binding 2.33192450173199 bayes_pls_golite062009
calcium-dependent protein binding 1.88288628726104 bayes_pls_golite062009
transporter activity 1.74189664015129 bayes_pls_golite062009
protein binding 1.61683263008775 bayes_pls_golite062009
substrate-specific transporter activity 1.49085442233849 bayes_pls_golite062009
protein transporter activity 1.29100730674261 bayes_pls_golite062009
transmembrane transporter activity 1.13101548288086 bayes_pls_golite062009
excitatory extracellular ligand-gated ion channel activity 0.86350507004267 bayes_pls_golite062009
extracellular ligand-gated ion channel activity 0.86350507004267 bayes_pls_golite062009
SNARE binding 0.71459772253941 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.643064875848901 bayes_pls_golite062009
gated channel activity 0.621670335227137 bayes_pls_golite062009
ligand-gated ion channel activity 0.41937155561589 bayes_pls_golite062009
ligand-gated channel activity 0.41937155561589 bayes_pls_golite062009
ion transmembrane transporter activity 0.370484918396857 bayes_pls_golite062009
channel activity 0.0647076360772156 bayes_pls_golite062009
passive transmembrane transporter activity 0.0647076360772156 bayes_pls_golite062009
substrate-specific channel activity 0.0435980899803177 bayes_pls_golite062009
phospholipid binding 0.0172309833091902 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle