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View Structure Prediction Details

Protein: nhx-4
Organism: Caenorhabditis elegans
Length: 749 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhx-4.

Description E-value Query
Range
Subject
Range
gi|28478878, gi|... - gi|75832049|ref|NP_001028461.2| solute carrier family 9 (sodium/hydrogen exchanger), member 2 [Mus m...
394.0 [0..33] [740..29]

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Predicted Domain #1
Region A:
Residues: [1-87]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSQKTLLVI LTLLLSYNVF CTGDTNGTLA QDPADQLLNT VPENFTNNIE YPQNNNNNTS  60
   61 ETDESMDAEG EWVQSAPPEE IEEAKHL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [88-579]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDPVHVDFEH THKPLAFVFL IILVTLAKPT LHWPVLRKLP ESVVLMLYGV LMATAVKALM  60
   61 RIDPGQLDTF MFFMILLPAI VNDAGLSMQK KEFTIALPKI LLFAVVGTVV HALLLAATMY 120
  121 GIEPIFSFKP GFLHLFVFAT LISAVDPVSV LSTFAELDVK KSLFILIFGE SLCNDAVTIV 180
  181 LYRTSINVIK TSDASDEMLT ITSVVGSCVV QFMIVCGFGL LCGAVVGFAG VFIMKNMVGH 240
  241 QMNQPIFQLF CPYLAYLLAE TGHYSGILAS ILCAAIMSYY MAANMCVEME FAAFTFSKTG 300
  301 SSLSESCIFF YLGVSLVSYN HEFDFYFIAV TVFCCTLYRF LVTCTLSAFY NLFASEKNRI 360
  361 PFTDQLVVTH AGIRGAVCFG LVQIIDERII PAKPYFVTTT LAMIFVTSIL QGCTIKFVMK 420
  421 CLKIPGDDGT KQKDPKALRW LTHLNDKYIK KFLVSENTYL PTDETFRNLG LPKAVSTALR 480
  481 IGERSHTDLQ RH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.39794
Match: 1fftA
Description: Cytochrome O ubiquinol oxidase, subunit I
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrogen ion transmembrane transporter activity 6.67219472356299 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 5.36696570788676 bayes_pls_golite062009
cation transmembrane transporter activity 4.97293291274237 bayes_pls_golite062009
ion transmembrane transporter activity 4.88027604120114 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 4.56139688972524 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 4.48195996846249 bayes_pls_golite062009
transporter activity 3.02642879486966 bayes_pls_golite062009
transmembrane transporter activity 2.89692543447799 bayes_pls_golite062009
substrate-specific transporter activity 2.65243944674297 bayes_pls_golite062009
binding 0.679485348721049 bayes_pls_golite062009
protein binding 0.358081002328109 bayes_pls_golite062009
heme-copper terminal oxidase activity 0.240598645883604 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [580-749]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEVSHTPAPS VGRPTIAPFD FGNMEEENNR LPSTGRRTPV ARSQTRYSRH FIYAIPNETD  60
   61 NYLTCPVSAS KRPPFDPSQV YQHQNTISNP GDDRARCYNR RHNSMSGADE MELKQLNQTV 120
  121 QKKLSRTITS GTKQFVVNPD EAIREESPAT IPKKRATFED DEISKIDESE 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle