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View Structure Prediction Details

Protein: lip-1
Organism: Caenorhabditis elegans
Length: 369 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lip-1.

Description E-value Query
Range
Subject
Range
gi|60099237 - gi|60099237|emb|CAH65449.1| hypothetical protein [Gallus gallus]
269.0 [0..5] [358..12]

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Predicted Domain #1
Region A:
Residues: [1-160]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTHLPSTSQ NGEEISAEQF NRIFHERNVI VLDCRSNGDS VKRANRFFCS LRLPALLQRR  60
   61 LMGGSMRLST VPDLKDLNNS PDQCPEVLLI PGDSEQDEQL SAALARNLKS NHYRHFVLGE 120
  121 PVKTLLSQFP TLRDAADENW NTTFQMNSMP GQASGQQASS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.522879
Match: 1hzmA
Description: Erk2 binding domain of Mapk phosphatase mkp-3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 4.79074052803751 bayes_pls_golite062009
phosphatase activity 3.95816335500141 bayes_pls_golite062009
phosphoric ester hydrolase activity 3.78173224935267 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 3.24681684836294 bayes_pls_golite062009
protein tyrosine phosphatase activity 2.84204105189999 bayes_pls_golite062009
hydrolase activity 2.12055507229256 bayes_pls_golite062009
binding 1.72957395505299 bayes_pls_golite062009
protein binding 1.56606332199727 bayes_pls_golite062009
catalytic activity 0.687308230067573 bayes_pls_golite062009
transferase activity 0.302497611306574 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [161-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GPLLNLNQLR LEGEDQGGKQ RAEFPVKLTN FLYLGNAETA KNRDVLKKYS ISHVINVTSN  60
   61 LPNTFEEDPN MRYLRISADD NASHNLTKFF PEAISFIDDA RRNDSACLVH CLAGISRSVT 120
  121 ICLAYLMKTE MCTLDSAYEW VQKRNASIAP NFHFMGQLTD YEKMLGLNSN RVGVSRQAVN 180
  181 FDVHFFCIFK LKKKEENSPE SRILAETAV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 38.69897
Match: 2hxpA
Description: No description for 2hxpA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle