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View Structure Prediction Details

Protein: CE29873
Organism: Caenorhabditis elegans
Length: 263 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE29873.

Description E-value Query
Range
Subject
Range
gi|73989304 - gi|73989304|ref|XP_851466.1| PREDICTED: similar to general transcription factor IIF, polypeptide 2 [...
341.0 [0..10] [263..113]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPTKRYSND VDCELAKRSI WLVKVPRYLS ELWDANEGNV VGKLQIGAQV ELHTAKGLIH  60
   61 PKPKEPTEGS SSTVTQPEAS EIPTEYSFIL HDVKSQTMSV LSEDKQGLGA DAPIKTGKLA 120
  121 IEGRIIKKAE CRPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1f3uA
Description: TFIIF beta subunit, Rap30
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 10.2797850053222 bayes_pls_golite062009
transcription initiation factor activity 6.22439849848084 bayes_pls_golite062009
RNA polymerase II transcription factor activity 4.06672086326535 bayes_pls_golite062009
transcription regulator activity 3.89911747857156 bayes_pls_golite062009
binding 2.17316238057078 bayes_pls_golite062009
transcription activator activity 2.12958061949296 bayes_pls_golite062009
protein binding 1.90482509358938 bayes_pls_golite062009
transcription coactivator activity 1.30173573105398 bayes_pls_golite062009
transcription factor binding 0.677361513203971 bayes_pls_golite062009
transcription cofactor activity 0.43974291826617 bayes_pls_golite062009
catalytic activity 0.304516551414824 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [135-263]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATSKYMKMKL AHIVKNTQPK KTVKMIEKAA VKFKPVSVHA EDMIKSKQKK DGAKTYRADR  60
   61 DVLRGALFKA FEKHSFYRLQ DLQQLLQQPV SYVKEVLQEI AVYNTAPPHK SLWCLKPEYC 120
  121 NYKVNAQSE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.0
Match: 1bbyA
Description: DNA-BINDING DOMAIN FROM HUMAN RAP30, NMR, MINIMIZED AVERAGE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 5.67074370996647 bayes_pls_golite062009
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.99681957904233 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
transcription activator activity 3.70589483230587 bayes_pls_golite062009
sequence-specific DNA binding 3.58179858678904 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
RNA polymerase II transcription factor activity 2.60738445921725 bayes_pls_golite062009
transcription repressor activity 2.22485867684613 bayes_pls_golite062009
DNA-directed RNA polymerase activity 1.82365519759474 bayes_pls_golite062009
RNA polymerase activity 1.82365519759474 bayes_pls_golite062009
transcription elongation regulator activity 1.81270943531115 bayes_pls_golite062009
protein binding 1.80415286835431 bayes_pls_golite062009
RNA binding 0.992043085614693 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.66743181561551 bayes_pls_golite062009
nucleotidyltransferase activity 0.237727660028553 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.23177057841536 bayes_pls_golite062009
positive transcription elongation factor activity 0.13524243942225 bayes_pls_golite062009
structural molecule activity 0.111941063082739 bayes_pls_golite062009

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