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View Structure Prediction Details

Protein: pqe-1
Organism: Caenorhabditis elegans
Length: 558 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pqe-1.

Description E-value Query
Range
Subject
Range
pqe-1 - status:Confirmed UniProt:Q10124 protein_id:AAM45370.1
394.0 [0..3] [558..18]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKRPTSSAS VDSNDDGVHI PAKRMAHASS VPGPSRSKPP MIGAVKNRPN HTEMLDKRNK  60
   61 ESEEKRRKDR DELERL

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.03
Match: 2grxC
Description: No description for 2grxC was found.

Predicted Domain #2
Region A:
Residues: [77-348]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNKKHTTEEE KIKMARLQNA LKVVGKAAGL KATVKKELTG SPAKKQKPAP AVPKILDFSV  60
   61 GRTFTAIRQT AIKLVFDTFL ERDSPNAARE AQEFELSIAK QYTDGQKYRI NIGHKVAALR 120
  121 KENTSGILEV NKNAVSHDKI LAGGPKDNCT VARGRKTHVD HRQLSIEKLH PLLLQFKLTT 180
  181 SELETNAYPM RRDGSTKAVS IADTVYTQNK KMFLDDYDMS RNCSRCNKEF KLSPNGTMIR 240
  241 STGICRYHNR GVAINGKRDT FRKRYSCCNE EF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.96
Match: 1pqvS
Description: RNA polymerase II-TFIIS complex
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [349-558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVALGCKFSD VHVTDQLFKK ELSTFVSTPV PVPNDQRSTR VYALDCEMVY TIAGPALARL  60
   61 TMVDMQRNRV LDVFVKPPTD VLDPNTEFSG LTMEQINSAP DTLKTCHQKL FKYVNADTIL 120
  121 IGHSLESDLK AMRVVHKNVI DTAILFRSTR DTKVALKVLS AKLLHKNIQG DNEDAIGHDS 180
  181 MEDALTCVDL IFYGLRNPES IAIREANTNC 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.69897
Match: 2guiA
Description: No description for 2guiA was found.

Predicted functions:

Term Confidence Notes
nuclease activity 2.65398446409354 bayes_pls_golite062009
ribonuclease activity 2.17677493546761 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 1.74431545836806 bayes_pls_golite062009
exoribonuclease activity 1.70600098208524 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.65911933935463 bayes_pls_golite062009
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1.59628511603826 bayes_pls_golite062009
hydrolase activity 1.52504970608306 bayes_pls_golite062009
exonuclease activity 1.4327316829508 bayes_pls_golite062009
3'-5'-exoribonuclease activity 1.42069917818896 bayes_pls_golite062009
catalytic activity 1.25233849524628 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.19753926150484 bayes_pls_golite062009
1.18236432793831 bayes_pls_golite062009
transcription regulator activity 1.10433412699603 bayes_pls_golite062009
nucleic acid binding 1.04079362397031 bayes_pls_golite062009
endonuclease activity 0.991569665925888 bayes_pls_golite062009
3'-5' exonuclease activity 0.86862629020506 bayes_pls_golite062009
DNA binding 0.860359347662869 bayes_pls_golite062009
binding 0.762139256580538 bayes_pls_golite062009
RNA binding 0.750194803368593 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.389326716045122 bayes_pls_golite062009
transcription factor activity 0.332903382446869 bayes_pls_golite062009
ribonuclease H activity 0.244270343650265 bayes_pls_golite062009
endoribonuclease activity 0.016619833072142 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle