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View Structure Prediction Details

Protein: nhx-2
Organism: Caenorhabditis elegans
Length: 627 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nhx-2.

Description E-value Query
Range
Subject
Range
gi|28478878, gi|... - gi|75832049|ref|NP_001028461.2| solute carrier family 9 (sodium/hydrogen exchanger), member 2 [Mus m...
414.0 [0..17] [623..67]

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Predicted Domain #1
Region A:
Residues: [1-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYVGAECEE EEKEYPSRYP IAYFEWENVK IPMTICLWLI GASIAKIIFN LIPHLNELFP  60
   61 DSALLIMIGL IIGIIFKLIG VNKNAFFLES EVFMLYLLPP LVFDAGYFMP ARQFFDNFGS 120
  121 ILCFAMIGTS FNIVAIALSL WAISLTGLFS VETPLMHMLL FGSVAADVDP VAVIVIFEEL 180
  181 KVNEVLFIAV FGESLLNDGV AVVLYRMFLT FSEIGTENLI TSDYINGGVS FLVVAFGGIG 240
  241 IGLLFAFLTS LVTRFARDEE VKVLNSVFIL ILPYTCYLCG ELFGLSSIMA IVFCGAAMRQ 300
  301 YCRENVDPDT VKATESFIKV LSLASETVIF VFLGLSTVSS NHHWDTSFIV LTVVFCLIYR 360
  361 TLGVVVMCYF LNKYRLNKYT KVDQFIMAYG GLRGAIAYGL VVAIPDFIPG KNMFVTSCII 420
  421 VIYFTVFLQG ITLKPIAEFL QVE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.04
Match: 1pw4A
Description: Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 3.29601790030287 bayes_pls_golite062009
ion transmembrane transporter activity 2.37005362941394 bayes_pls_golite062009
transporter activity 2.27206061444828 bayes_pls_golite062009
cation transmembrane transporter activity 2.08122979774613 bayes_pls_golite062009
transmembrane transporter activity 1.76993243926717 bayes_pls_golite062009
substrate-specific transporter activity 1.49938666401349 bayes_pls_golite062009
binding 0.368477568387728 bayes_pls_golite062009
active transmembrane transporter activity 0.206030814887517 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [444-627]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KKNVHSKNMI EHIYSELIDT TMAGMEDIAG FKGHHWIRDS WNALNNNYLR PILVNKNNMK  60
   61 EMDKTKLVRK YKHLVDEDAK KIARGDLNSN MVFTKALIEH TRSRTNTMID GVSSTSKIDF 120
  121 TKHMKENFGV TVYDDHSTVP MTPTHLFQET TEVEYSVRSE INDNDGFEND GYESDESGSF 180
  181 HERV

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.55
Match: 1jadA
Description: C-terminal domain of PLC-beta
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle