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View Structure Prediction Details

Protein: egl-5
Organism: Caenorhabditis elegans
Length: 219 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-5.

Description E-value Query
Range
Subject
Range
gi|47971146 - gi|47971146|dbj|BAD22530.1| LjHox5i Homeobox [Lethenteron japonicum]
133.0 [0..87] [171..1]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTSTSAFDF GSSTASSAAT STTSSQPDAN DHLSRLAAMT QGVGKEDPET SSTPSTEASL  60
   61 YPGISAAYMQ SYGWPQNYNY FGQPLGPATF PG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [93-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WPQCYPNTAW PNYASSKKGR QTYQRYQTSV LEAKFQQSSY VSKKQREELR LQTQLTDRQI  60
   61 KIWFQNRRMK AKKEKQRVDD HTEHTPLLPA NPPKGMGMDM DDEKKWQMAH WPPAAAHNPY 120
  121 QYPLCPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.522879
Match: 1b8iA
Description: Ultrabithorax (ubx) homeodomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.57523737355937 bayes_pls_golite062009
DNA binding 3.00143272905695 bayes_pls_golite062009
nucleic acid binding 2.89825020286436 bayes_pls_golite062009
transcription factor activity 2.53664874743748 bayes_pls_golite062009
transcription repressor activity 1.84054423341798 bayes_pls_golite062009
binding 1.68817361068715 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.14821760889085 bayes_pls_golite062009
sequence-specific DNA binding 0.46503550280898 bayes_pls_golite062009
protein binding 0.111941607625758 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle