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View Structure Prediction Details

Protein: egl-5
Organism: Caenorhabditis elegans
Length: 219 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-5.

Description E-value Query
Range
Subject
Range
gi|47971146 - gi|47971146|dbj|BAD22530.1| LjHox5i Homeobox [Lethenteron japonicum]
133.0 [0..87] [171..1]

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Predicted Domain #1
Region A:
Residues: [1-92]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTSTSAFDF GSSTASSAAT STTSSQPDAN DHLSRLAAMT QGVGKEDPET SSTPSTEASL  60
   61 YPGISAAYMQ SYGWPQNYNY FGQPLGPATF PG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [93-219]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WPQCYPNTAW PNYASSKKGR QTYQRYQTSV LEAKFQQSSY VSKKQREELR LQTQLTDRQI  60
   61 KIWFQNRRMK AKKEKQRVDD HTEHTPLLPA NPPKGMGMDM DDEKKWQMAH WPPAAAHNPY 120
  121 QYPLCPP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.522879
Match: 1b8iA
Description: Ultrabithorax (ubx) homeodomain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.57523737355937 bayes_pls_golite062009
DNA binding 3.00143272905695 bayes_pls_golite062009
nucleic acid binding 2.89825020286436 bayes_pls_golite062009
transcription factor activity 2.53664874743748 bayes_pls_golite062009
transcription repressor activity 1.84054423341798 bayes_pls_golite062009
binding 1.68817361068715 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.14821760889085 bayes_pls_golite062009
sequence-specific DNA binding 0.46503550280898 bayes_pls_golite062009
protein binding 0.111941607625758 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle