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View Structure Prediction Details

Protein: kap-1
Organism: Caenorhabditis elegans
Length: 679 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for kap-1.

Description E-value Query
Range
Subject
Range
kap-1 - status:Confirmed UniProt:Q8MYQ8 protein_id:AAM22059.1
341.0 [0..1] [679..1]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQVSIDAHP SDQAIIVRFE QSPTNVESLG HQKIIHLKEM SLDVDIRALS NVILQKCLFI  60
   61 PATSRSQLEQ VLFYIQKRGN QRISARSRSS SAVSFDR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.30103
Match: 1gw5B
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [98-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RPIHSPTISA ELGKIDEYIE CFYGETSVEK NKGAVALYEL SKNPQNLTQL VNNETLMMAL  60
   61 ARVFREDWKK HFEVGTNIMN LFIGTLCVNA MEHETKRYDF WIAEMKKTDQ ETLRKLKTAI 120
  121 RKQAMLLAAC VTFLTNLATD ISVELKMVRR NLVALLVKCL QMSSESTSSL TTATIKFLLK 180
  181 LSIFDENKIV MEQNGTIEKL LKLFPIQDPE LRKAVIMLLF NFSFDSKNLP KMVNGGLVPH 240
  241 MASLLDSDTK ALNMMYLLSC NDDAKAMLAY TDAIKLLMKD VLSGTGSEVT KAVLLNICLE 300
  301 KRNAQLVCGQ RGQGLDLLME MSINSRDLML IKVVRAISSH EGATQNMFLK WIETLIGIAK 360
  361 NEGADNSESK SSFGLECMGT VAELKVAPWA KIIQSENLVP WMKTQLQEGI DESEEVTVLR 420
  421 DIKPLQLQIV IACGTMARQL DAARLLAPLI DTFVQLLQSC QIDDEFVVQL LYVFLQFLKH 480
  481 KELSARLMTQ DSALGAHMID LMHDANAVVR EVCDNALLIM GEHSKEWAKR IAGERFKWHN 540
  541 AQWLEMVERD DSEFVDYDDE DFGADLKFDH YDDGFDMNEP LF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 2gl7A
Description: No description for 2gl7A was found.

Predicted functions:

Term Confidence Notes
protein transporter activity 3.05338750264476 bayes_pls_golite062009
protein binding 2.78733902345842 bayes_pls_golite062009
binding 2.6374633159018 bayes_pls_golite062009
transporter activity 1.55621630624352 bayes_pls_golite062009
substrate-specific transporter activity 1.33334123659384 bayes_pls_golite062009
cytoskeletal protein binding 1.23804310697631 bayes_pls_golite062009
protein transmembrane transporter activity 1.15447282085461 bayes_pls_golite062009
enzyme regulator activity 0.698613639309592 bayes_pls_golite062009
nucleic acid binding 0.425403776087115 bayes_pls_golite062009
actin binding 0.360199499297314 bayes_pls_golite062009
transmembrane transporter activity 0.350388174853674 bayes_pls_golite062009
signal sequence binding 0.27824906981293 bayes_pls_golite062009
cell adhesion molecule binding 0.237512539263598 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.141331164449492 bayes_pls_golite062009
nucleoside-triphosphatase regulator activity 0.0332743336452223 bayes_pls_golite062009
RNA binding 0.0287526191298597 bayes_pls_golite062009
GTPase regulator activity 0.0268373969988844 bayes_pls_golite062009
guanyl ribonucleotide binding 0.00234756529236324 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle