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View Structure Prediction Details

Protein: CE27834
Organism: Caenorhabditis elegans
Length: 414 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE27834.

Description E-value Query
Range
Subject
Range
gi|7497168 - gi|7497168|pir||T25623 hypothetical protein C37H5.13 - Caenorhabditis elegans
493.0 [0..1] [414..1]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVGCRTARH FVKSTARRFI EQKRLESLTT GNGMSSPSST HANTAPVVQS HFAHRPQHVS  60
   61 SAPSRSMEID DQNGVQHYPM LLNVTHIDMT SRADDIRAGL IDTFL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [106-414]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NLERVDKNLY LARHLLKGRN SLPVVYGGQV IGQALSAATA TVEVGFVPNS LHSYFVQSGN  60
   61 VERPILYQVD RIRDGKSFCT RLVKALQDGE AIFTVQISFH RPEADSIVHQ LPMPEVPAPD 120
  121 SLEDLSDTFE RIKKNANIPP AALAMIGFKQ KEIPPAFFRI FSFRPVDIDS YLCLKKDDHT 180
  181 AGHGHPTDAY RSYVWIKANE NIGDDPRLHL AAAAYISDAT MIETALRPHS KRGFIPSMAL 240
  241 TLDHSIWMHT DNFRVDDWML YENHSTIAGG GRSLIEGKLW TRDGRLVFST TQEALIRTAK 300
  301 NRPNASPAK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 79.0
Match: 1c8uA
Description: Thioesterase II (TesB)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acyl-CoA thioesterase activity 2.60197973503923 bayes_pls_golite062009
CoA hydrolase activity 2.3187640589669 bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity 1.14159464719086 bayes_pls_golite062009
thiolester hydrolase activity 1.14125301545576 bayes_pls_golite062009
catalytic activity 0.74605540351792 bayes_pls_golite062009
binding 0.358549779743531 bayes_pls_golite062009
hydrolase activity 0.093543122203219 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle