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Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor. Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: 3-hydroxyacyl-CoA dehydrogenase activity
Acc: GO:0003857
Aspect: Molecular Function
Desc: Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H+.
Synonyms:
  • beta-hydroxyacyl dehydrogenase activity
  • beta-hydroxyacyl-coenzyme A synthetase activity
  • L-3-hydroxyacyl CoA dehydrogenase activity
  • beta-hydroxyacylcoenzyme A dehydrogenase activity
  • beta-keto-reductase activity
  • L-3-hydroxyacyl coenzyme A dehydrogenase activity
  • beta-hydroxybutyrylcoenzyme A dehydrogenase activity
  • beta-ketoacyl-CoA reductase
Proteins in PDR annotated with:
   This term: 48 [Search]
   Term or descendants: 48 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity (interactive image map)

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