| Protein: | lin-2 |
| Organism: | Caenorhabditis elegans |
| Length: | 620 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for lin-2.
| Description | E-value | Query Range |
Subject Range |
|
|
422.0 | [0..1] | [620..1] |
|
Region A: Residues: [1-100] |
1 11 21 31 41 51
| | | | | |
1 MSSAATPPPM EHTSSEDSTT APLQTPSSSS CLDVTVAVGT SVSYLKASPL VSSPTSLVVD 60
61 ITESSSTLLY DKIKALPCEP VVTEVDTSTL RKETLNQIDG
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [101-194] |
1 11 21 31 41 51
| | | | | |
1 LLGPSPEALE LRQLLNSPHL ASCVQALDVV VCEIRDPKNE ASGSGDKEGN CVSSDPAPAY 60
61 LNGGVLPLGA QRAGTSFEHF NQSAVHTSYD EEEE
|
| Detection Method: | |
| Confidence: | 14.568636 |
| Match: | PF02828.7 |
| Description: | No description for PF02828.7 was found. |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [195-292] |
1 11 21 31 41 51
| | | | | |
1 ELYDCMSRLR LVQFQKDTQE PMGITLKVNE DGRCFVARIM HGGMIHRQAT LHVGDEIREI 60
61 NGMSVANRSV ESLQEMLRDA RGQVTFKIIP SYRSAPPA
|
| Detection Method: | |
| Confidence: | 17.69897 |
| Match: | 1kwaA |
| Description: | Cask/Lin-2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.2595117613307 | bayes_pls_golite062009 |
| nucleobase, nucleoside, nucleotide kinase activity | 3.03529700765506 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.83180079733297 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.39826531242265 | bayes_pls_golite062009 |
| protein binding | 2.35875654816667 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.22344653950083 | bayes_pls_golite062009 |
| nucleotide kinase activity | 1.79696347300128 | bayes_pls_golite062009 |
| guanylate kinase activity | 1.70730560221787 | bayes_pls_golite062009 |
| phosphotransferase activity, phosphate group as acceptor | 1.69528181005421 | bayes_pls_golite062009 |
| signal transducer activity | 1.51162321843898 | bayes_pls_golite062009 |
| molecular transducer activity | 1.51162321843898 | bayes_pls_golite062009 |
| PDZ domain binding | 1.4161955255054 | bayes_pls_golite062009 |
| actin binding | 0.734175820477621 | bayes_pls_golite062009 |
| protein domain specific binding | 0.64214865642772 | bayes_pls_golite062009 |
| transcription regulator activity | 0.387065538161985 | bayes_pls_golite062009 |
| receptor binding | 0.359972518335054 | bayes_pls_golite062009 |
| structural molecule activity | 0.339803285888713 | bayes_pls_golite062009 |
|
Region A: Residues: [293-414] |
1 11 21 31 41 51
| | | | | |
1 CEIFVRAQFD YEPSQDDLIP CPQAGIPFKT GDILQVISKD DHNWWQARFV SSFPSIGNSS 60
61 NAQRSNQQQV AGLIPSPELQ EWRTACLAME RSKNTCNTHC MWFNKKKKYY TTKYLQKHSA 120
121 LF
|
| Detection Method: | |
| Confidence: | 3.88 |
| Match: | 1vytA |
| Description: | beta3 subunit complexed with aid |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.96288334076272 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.90420281193896 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.82087628734305 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 2.51719769231912 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 2.42590326752843 | bayes_pls_golite062009 |
| protein binding | 1.92580716027275 | bayes_pls_golite062009 |
| signal transducer activity | 1.78618922267834 | bayes_pls_golite062009 |
| molecular transducer activity | 1.78618922267834 | bayes_pls_golite062009 |
| actin binding | 1.78444456344995 | bayes_pls_golite062009 |
| actin filament binding | 0.697156220996695 | bayes_pls_golite062009 |
| structural molecule activity | 0.367876817922396 | bayes_pls_golite062009 |
|
Region A: Residues: [415-620] |
1 11 21 31 41 51
| | | | | |
1 DQLDLVTYEE VMRLSQYRRK TLVLLGAHGV GRRHIKNTLI HRHPNRFAYP IPHTTRPPRK 60
61 DEVDGKHYYF VTNEQMMADI QNNEYLEYGT HEESMYGTKL ETIRNIHKSG KIAILDVEPQ 120
121 ALKVLRTAEY SPFVVFIAAP NLQGMQDPDG SLEKLLNESD VLRQAFGHLF DFIITNSDID 180
181 DTIAQLERLV EKLPAYPQWL PVTWVY
|
| Detection Method: | |
| Confidence: | 37.0 |
| Match: | 1kgdA |
| Description: | Guanylate kinase-like domain of Cask |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 4.94368959158184 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 4.00431985024242 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 3.98749135039029 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 3.88411242531695 | bayes_pls_golite062009 |
| nucleobase, nucleoside, nucleotide kinase activity | 3.66392587433723 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 3.4124368949006 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 3.212476179089 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 3.0687919953843 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 3.01973954110645 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleotide kinase activity | 2.24094813695083 | bayes_pls_golite062009 |
| phosphotransferase activity, phosphate group as acceptor | 1.96697952975573 | bayes_pls_golite062009 |
| motor activity | 1.55763083999583 | bayes_pls_golite062009 |
| molecular transducer activity | 1.13474466330485 | bayes_pls_golite062009 |
| signal transducer activity | 1.13474466330485 | bayes_pls_golite062009 |
| nucleic acid binding | 1.08697924060619 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.03255157977314 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| guanylate kinase activity | 0.98934362137863 | bayes_pls_golite062009 |
| microtubule motor activity | 0.84931691607013 | bayes_pls_golite062009 |
| DNA binding | 0.702147676354075 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.489050800152752 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.485303203507997 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.482413717607895 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.457886666766291 | bayes_pls_golite062009 |
| adenylate kinase activity | 0.447752711852745 | bayes_pls_golite062009 |
| purine nucleotide binding | 0.442941451960958 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 0.440672169804309 | bayes_pls_golite062009 |
| ribonucleotide binding | 0.440612929099368 | bayes_pls_golite062009 |
| nucleotide binding | 0.433111366205869 | bayes_pls_golite062009 |
| receptor activity | 0.381142123108547 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.355770151889237 | bayes_pls_golite062009 |
| actin binding | 0.351722091343607 | bayes_pls_golite062009 |
| transcription regulator activity | 0.312171320541728 | bayes_pls_golite062009 |
| proton-transporting ATPase activity, rotational mechanism | 0.20818362273204 | bayes_pls_golite062009 |
| GTPase activity | 0.20128275658561 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of ions | 0.0871526397126998 | bayes_pls_golite062009 |
| helicase activity | 0.0775311459068899 | bayes_pls_golite062009 |
