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View Structure Prediction Details

Protein: rpn-10
Organism: Caenorhabditis elegans
Length: 346 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpn-10.

Description E-value Query
Range
Subject
Range
gi|114559348 - gi|114559348|ref|XP_001170036.1| PREDICTED: similar to PSMD4P2 protein isoform 1 [Pan troglodytes]
333.0 [0..10] [343..523]

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Predicted Domain #1
Region A:
Residues: [1-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQESTMICV DNSEYMRNGD FQPTRLQSQQ DAVNLVTQCK LRANPENAVG ILSMANSVQV  60
   61 LSSLSTEQGR LMMKNHSIEP FGKCNFIAGI KIAHLALKHR QNRNHKMRVV LFIGSPLEEI 120
  121 EMNELVKIAK KMKKEKVLCD VIMFGENESD GHEKFSTFVD TLNGKEGSGS SLIVVPQGSS 180
  181 LTDALLQSSV C

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1n3yA
Description: Integrin alpha-x beta2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 4.02098822555334 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 3.82496592594463 bayes_pls_golite062009
endopeptidase activity 3.72596563304893 bayes_pls_golite062009
binding 3.32950434867692 bayes_pls_golite062009
hydrolase activity 2.72944528058473 bayes_pls_golite062009
protein binding 1.4332924081006 bayes_pls_golite062009
nucleic acid binding 1.41389987484225 bayes_pls_golite062009
DNA binding 1.27751137443334 bayes_pls_golite062009
transporter activity 0.778626141603949 bayes_pls_golite062009
protein dimerization activity 0.45109468643752 bayes_pls_golite062009
enzyme binding 0.39062208299171 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.0661625326929309 bayes_pls_golite062009
protein complex binding 0.0341925447010603 bayes_pls_golite062009
pyrophosphatase activity 0.027305897174472 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0179622467180781 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.0153681945260867 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [192-346]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNEDGQAAFG GGGNGMDNAF GMDVENDPDL ALALRVSMEE ERARQAAAAA ANGGAADSGA  60
   61 DAEVAAAAAA VPLEEMDMGA MTEEQQLEWA LRLSMQENAP AEQPQVQHEQ MDVDGAPAVG 120
  121 GDNLDDLMNN PELLQQIVDD LPAANAEKDD DKEKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.69897
Match: 1yx4A
Description: Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle