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View Structure Prediction Details

Protein: map-2
Organism: Caenorhabditis elegans
Length: 444 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for map-2.

Description E-value Query
Range
Subject
Range
gi|114646288 - gi|114646288|ref|XP_509279.2| PREDICTED: similar to Chain , Human Methionine Aminopeptidase 2 [Pan ...
338.0 [0..73] [444..139]

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Predicted Domain #1
Region A:
Residues: [1-68]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPANGKKGK KGGAAKAAAP EEDFDAILAE MQLADAKTAA KEATKKDAKG GKGKANGSAA  60
   61 ATAAPEEA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.522879
Match: 1a16A
Description: AMINOPEPTIDASE P FROM E. COLI WITH THE INHIBITOR PRO-LEU
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [69-444]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQAWQAEIAA MKPIDEQFPD GKFPHGIDES PYYLKGKDGR VATDRESNEE KKALDISYEE  60
   61 VWQDYRRSAE AHRQVRKYVK SWIKPGMTMI EICERLETTS RRLIKEQGLE AGLAFPTGCS 120
  121 LNHCAAHYTP NAGDTTVLQY GDVCKIDYGI HVRGRLIDSA FTVHFDPKFD PLVEAVREAT 180
  181 NAGIKESGID VRLCDVGEIV EEVMTSHEVE LDGKSYVVKP IRNLNGHSIA QYRIHAGKTV 240
  241 PIVKGGEQTK MEENEIYAIE TFGSTGKGYV HDDMETSHYM KNFELADEKI PLRLQKSKGL 300
  301 LNLIDKNFAT LAFCRRWIDR LGETKYLMAL KDLCDKGIVD PYPPLCDVKG CYTAQWEHTI 360
  361 LMRPTVKEVV SRGDDY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 92.221849
Match: 1b6aA
Description: HUMAN METHIONINE AMINOPEPTIDASE 2 COMPLEXED WITH TNP-470
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
peptidase activity 2.60615909541559 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 2.18503136472662 bayes_pls_golite062009
sequence-specific DNA binding 2.08341148210578 bayes_pls_golite062009
transcription activator activity 1.98504395280033 bayes_pls_golite062009
hydrolase activity 1.43646476372001 bayes_pls_golite062009
binding 1.2577767263541 bayes_pls_golite062009
transcription repressor activity 1.05292713355237 bayes_pls_golite062009
aminopeptidase activity 0.89399203910285 bayes_pls_golite062009
exopeptidase activity 0.762255574851485 bayes_pls_golite062009
metallopeptidase activity 0.629480947971878 bayes_pls_golite062009
nucleic acid binding 0.478507702690501 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.42135864069093 bayes_pls_golite062009
transcription regulator activity 0.377243230296854 bayes_pls_golite062009
catalytic activity 0.148551873544128 bayes_pls_golite062009
DNA binding 0.146627179138465 bayes_pls_golite062009
protein binding 0.0709708941336981 bayes_pls_golite062009
transferase activity 0.064832527337659 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 6.94228632297178E-4 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle