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View Structure Prediction Details

Protein: mys-1
Organism: Caenorhabditis elegans
Length: 458 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mys-1.

Description E-value Query
Range
Subject
Range
gi|76658150 - gi|76658150|ref|XP_887601.1| PREDICTED: similar to HIV-1 Tat interactive protein, 60kDa isoform 1 is...
480.0 [0..9] [452..14]

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Predicted Domain #1
Region A:
Residues: [1-161]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEPKKEIIE DENHGISKKI PTDPRQYEKV TEGCRLLVMM ASQEEERWAE VISRCRAANG  60
   61 SIKFYVHYID CNRRLDEWVQ SDRLNLASCE LPKKGGKKGA HLREENRDSN ENEGKKSGRK 120
  121 RKIPLLPMDD LKAESVDPLQ AISTMTSGST PSLRGSMSMV G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.39794
Match: 1wgsA
Description: Solution Structure of the Tudor Domain from Mouse Hypothetical Protein Homologous to Histone Acetyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription repressor activity 4.08500855631983 bayes_pls_golite062009
chromatin binding 3.84065302930105 bayes_pls_golite062009
transcription regulator activity 3.64390820819794 bayes_pls_golite062009
methylated histone residue binding 3.42338304360938 bayes_pls_golite062009
binding 3.06758476214113 bayes_pls_golite062009
protein binding 2.66728689880621 bayes_pls_golite062009
transcription elongation regulator activity 2.46353586381231 bayes_pls_golite062009
nucleic acid binding 2.19167058827256 bayes_pls_golite062009
DNA binding 2.05514577638135 bayes_pls_golite062009
histone binding 2.00388175060339 bayes_pls_golite062009
transcription activator activity 1.46529895769882 bayes_pls_golite062009
sequence-specific DNA binding 1.10020047862576 bayes_pls_golite062009
DNA-dependent ATPase activity 0.998957812785999 bayes_pls_golite062009
general transcriptional repressor activity 0.75184432495983 bayes_pls_golite062009
DNA helicase activity 0.726970683178132 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.494788451379878 bayes_pls_golite062009
transcription corepressor activity 0.294457188332415 bayes_pls_golite062009
catalytic activity 0.14067200158938 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [162-458]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HSEDAMTRIR NVECIELGRS RIQPWYFAPY PQQLTSLDCI YICEFCLKYL KSKTCLKRHM  60
   61 EKCAMCHPPG NQIYSHDKLS FFEIDGRKNK SYAQNLCLLA KLFLDHKTLY YDTDPFLFYV 120
  121 LTEEDEKGHH IVGYFSKEKE SAEEYNVACI LVLPPFQKKG YGSLLIEFSY ELSKIEQKTG 180
  181 SPEKPLSDLG LLSYRSYWSM AIMKELFAFK RRHPGEDITV QDISQSTSIK REDVVSTLQQ 240
  241 LDLYKYYKGS YIIVISDEKR QVYEKRIEAA KKKTRINPAA LQWRPKEYGK KRAQIMF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 107.0
Match: 2ou2A
Description: No description for 2ou2A was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle