YRC Public Data Repository - Protein Structure Prediction

Protein:	CE19036
Organism:	Caenorhabditis elegans
Length:	260 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE19036.

Description	E-value	Query Range	Subject Range
gi\|115891513, gi... - gi\|115949376\|ref\|XP_001191822.1\| PREDICTED: similar to hydroxyacyl glutathione hydrolase [Strongyloc...	230.0	[0..2]	[260..1]
CG4365-PC - This gene is referred to in FlyBase by the symbol Dmel\CG4365 (CG4365, FBgn0037024). It is a protein...	229.0	[0..2]	[260..90]
gi\|125977966, gi... - gi\|54641767\|gb\|EAL30517.1\| GA18136-PA [Drosophila pseudoobscura], gi\|125977966\|ref\|XP_001353016.1\| G...	226.0	[0..2]	[260..84]
gi\|66911967 - gi\|66911967\|gb\|AAH97301.1\| Hagh protein [Rattus norvegicus]	225.0	[0..1]	[260..44]
gi\|110758324 - gi\|110758324\|ref\|XP_623458.2\| PREDICTED: similar to hydroxyacylglutathione hydrolase isoform 1 [Apis...	225.0	[0..2]	[260..34]
GLO2_SYNE7 - Hydroxyacylglutathione hydrolase OS=Synechococcus elongatus (strain PCC 7942) GN=gloB PE=3 SV=1 GLO2_SYNP6 - Hydroxyacylglutathione hydrolase OS=Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1) G...	223.0	[0..2]	[260..1]
gi\|16209608 - gi\|16209608\|gb\|AAL14249.1\| glyoxalase II [Oryza sativa] gi\|113631906, gi... - gi\|50726249\|dbj\|BAD33825.1\| glyoxalase II [Oryza sativa Japonica Group], gi\|215737215\|dbj\|BAG96144.1... gi\|218202459 - gi\|218202459\|gb\|EEC84886.1\| hypothetical protein OsI_32046 [Oryza sativa Indica Group]	222.0	[0..2]	[260..83]
gi\|28143946 - gi\|28143946\|gb\|AAO26580.1\| glyoxalase II [Brassica juncea]	222.0	[0..2]	[260..82]

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Predicted Domain #1

Region A:
Residues: [1-260]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYVKSLLRR ADNFMYIVKK SSEARAALLV DLVNEEDYKE LADKENIDIT AVLTTHHHYD  60
   61 HCGGNEGFRR QFPNVMILGG DSRIPAMDRH VKHGDMAEFA GLQIKCLSTP CHTSGHICYH 120
  121 ITNPAADSTS PGVVFTGDTL FIAGCGRFFE GTAPQMDVAL NEILKNLPVE TQIFPGHEYT 180
  181 VANLKFACHV EPGNEKAAQK LEWAQRQIEQ GGFTVPSTVA EEKATNPFMR VRESEEIQKS 240
  241 IGTCDAVVGM AKLREMKNKF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.0
Match:	1qh3A
Description:	Glyoxalase II (hydroxyacylglutathione hydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydroxyacylglutathione hydrolase activity	3.53012507604564	bayes_pls_golite062009
catalytic activity	0.941400907161877	bayes_pls_golite062009
binding	0.900972948435178	bayes_pls_golite062009
thiolester hydrolase activity	0.802604883362264	bayes_pls_golite062009
hydrolase activity	0.021392930321391	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: