YRC Public Data Repository - Protein Structure Prediction

Protein:	CE18143
Organism:	Caenorhabditis elegans
Length:	227 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE18143.

Description	E-value	Query Range	Subject Range
gi\|115391327, gi... - gi\|115391327\|ref\|XP_001213168.1\| ribose-phosphate pyrophosphokinase 2 [Aspergillus terreus NIH2624],...	186.0	[0..1]	[221..76]
gi\|114687774 - gi\|114687774\|ref\|XP_001134786.1\| PREDICTED: similar to mKIAA0316 protein [Pan troglodytes]	186.0	[0..1]	[221..493]
gi\|117607884, gi... - gi\|69256563\|ref\|ZP_00606057.1\| Ribose-phosphate pyrophosphokinase [Magnetococcus sp. MC-1], gi\|68247...	185.0	[0..1]	[220..76]
KPRS_RALSO - Ribose-phosphate pyrophosphokinase OS=Ralstonia solanacearum GN=prs PE=3 SV=1 KPRS_RALSO - Ribose-phosphate pyrophosphokinase OS=Ralstonia solanacearum (strain GMI1000) GN=prs PE=3 SV=1	185.0	[0..1]	[221..75]
gi\|77545683, gi\|... - gi\|77919600\|ref\|YP_357415.1\| phosphoribosyl pyrophosphate synthetase [Pelobacter carbinolicus DSM 23...	185.0	[0..1]	[221..73]
gi\|85722821, gi\|... - gi\|85859730\|ref\|YP_461932.1\| ribose-phosphate pyrophosphokinase [Syntrophus aciditrophicus SB], gi\|8...	184.0	[0..1]	[220..74]
gi\|66849382, gi\|... - gi\|70993802\|ref\|XP_751748.1\| phosphoribosyl diphosphate synthase isoform 4 [Aspergillus fumigatus Af... gi\|159125332 - gi\|159125332\|gb\|EDP50449.1\| phosphoribosyl diphosphate synthase isoform 4 [Aspergillus fumigatus A11...	184.0	[0..1]	[221..76]
gi\|67523017, gi\|... - gi\|67523017\|ref\|XP_659569.1\| hypothetical protein AN1965.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	182.0	[0..1]	[221..76]
gi\|67154369, gi\|... - gi\|67154369\|ref\|ZP_00416114.1\| Ribose-phosphate pyrophosphokinase [Azotobacter vinelandii AvOP], gi\|... gi\|67154369 - gi\|67154369\|ref\|ZP_00416114.1\| Ribose-phosphate pyrophosphokinase [Azotobacter vinelandii AvOP]	182.0	[0..1]	[221..116]
gi\|73540048, gi\|... - gi\|73540048\|ref\|YP_294568.1\| ribose-phosphate pyrophosphokinase [Ralstonia eutropha JMP134], gi\|7211...	182.0	[0..1]	[221..75]

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Predicted Domain #1

Region A:
Residues: [1-227]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAATATANG NHSIEDPVVM KVQAASPIQE TDFFENLYQM ECFRTGEFYL KSGQMTPIYI  60
   61 DLRRIMSSPR VLRMAAQAMC EKIVASNLKF DYVVGVPYAA LPLATLVSDI LNVPMLMKRK 120
  121 EAKAYGTKQL IEGVYQPGGT VLLVEDVVTS GESIRETAEA IRNENLLVTD AIAVLDRQQG 180
  181 ATANLAEDNL NFLSFLTMEK ILDGLITKNE MTEERKHEII AHLAKPF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.0
Match:	1oroA
Description:	Orotate PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
adenine phosphoribosyltransferase activity	3.1748712918814	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	3.0470646511978	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	2.97347277288245	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.21367942706564	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	2.02298774328915	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.51875493459374	bayes_pls_golite062009
nucleobase binding	1.28671115202467	bayes_pls_golite062009
purine binding	1.24786927434743	bayes_pls_golite062009
amidophosphoribosyltransferase activity	0.932396739123353	bayes_pls_golite062009
binding	0.847513071499147	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
nucleic acid binding	0.552133387792911	bayes_pls_golite062009
DNA binding	0.439741935655503	bayes_pls_golite062009
transcription regulator activity	0.396538943915776	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: