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View Structure Prediction Details

Protein: prp-21
Organism: Caenorhabditis elegans
Length: 655 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for prp-21.

Description E-value Query
Range
Subject
Range
gi|55244637, gi|... - gi|58376969|ref|XP_309321.2| ENSANGP00000008201 [Anopheles gambiae str. PEST], gi|55244637|gb|EAA051...
644.0 [0..21] [655..1]

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Predicted Domain #1
Region A:
Residues: [1-110]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAVVSNREE DSMNNEPSLS GRAIIGLIYP PPDIRTIVDK TARFAAKNGV DFENKIREKE  60
   61 AKNPKFNFLS ITDPYHAYYK KMVYDFSEGR VEAPKVPQAV KEHVKKAEFV 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.39794
Match: 2dt6A
Description: No description for 2dt6A was found.

Predicted Domain #2
Region A:
Residues: [111-201]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSAPPPAYEF SADPSTINAY DLDLIRLVAL FVARNGRQFL TQLMTREARN YQFDFLKPAH  60
   61 CNFTYFTKLV DQYQKVLVPS TNVVAQLQDD A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 24.221849
Match: 2dt7B
Description: No description for 2dt7B was found.

Predicted Domain #3
Region A:
Residues: [202-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNKKRLIEDI NYRVSWEKHQ KGLKDREEAE AEKERQAYAS IDWHDFVVVQ TVDFQPGDTS  60
   61 QLPPLCTPKD VGARILLEAR NEMQKAAAEM QEMDMEESDS DDEDAVQAPE APAFTAPLPP 120
  121 TKQKDVIVRD YDPKRNVTQK PKAVENWIIS PLTGERIPSD KLAEHVRYNT VDSQYKEDRD 180
  181 RHIGERSTEE PVLALGADIS RNLGNFAER

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [411-530]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTDIFGVGGE QTMIGKKLGE EDNSQQGQNK LIWDGTEETR DMITRAVQNK VTLDQQINEI  60
   61 HRQHGFVADP SKEKIGAQQV PRHQSTQGNV TITQGITNIP GQMPSGWPPV PPMGMPGMPN 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [531-655]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QALPPIRQMD FGGGPPAKRP RTEDDLIPEA DWLKKVNGAI SLNVHLPQAP EHGMDGSIVQ  60
   61 FTIQVTAPMS ELKQQIQDRY GMPVGKQKLM SDGLFVKDNM SSAFYNLADR TAIYLQVKER 120
  121 GGKKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 26.522879
Match: 1we7A
Description: Solution structure of Ubiquitin-like domain in SF3a120
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 2.5865157751042 bayes_pls_golite062009
binding 2.19381585790185 bayes_pls_golite062009
structural constituent of ribosome 1.967509006593 bayes_pls_golite062009
protein binding 1.89134588490127 bayes_pls_golite062009
structural molecule activity 1.52853261170163 bayes_pls_golite062009
transcription regulator activity 1.11533445164506 bayes_pls_golite062009
nucleic acid binding 0.896431097217265 bayes_pls_golite062009
DNA binding 0.859811565165317 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle