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View Structure Prediction Details

Protein: npp-18
Organism: Caenorhabditis elegans
Length: 363 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for npp-18.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
339.0 [0..1] [360..1240]

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Predicted Domain #1
Region A:
Residues: [1-363]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQEDDSVKPF QTVGAHRDLI HCVSFDPHGR RMATCASDMT MAIWDRKPDG NWRRSAHWKC  60
   61 HGGAVWRVIW AHPEFGQIVA TCSYDRTIVI WEEQIVRSEK DLKQKESQWI RRTIISDNRS 120
  121 DVTDICFSPR HLGLMMASCN VLGTVRIYEA PDIVDASRWN LIHELQAFHT RCGCVTWSLS 180
  181 RMHRPLIAVG SDEKKAENKK RVVIYENIDG LRKWQRINSL VFDLPCPITD LKFSPISMVD 240
  241 SHQLAVASGD VHVYNIKVAR SAILEEDGVE NPIQLADYNL IKVALLGDHR KAWRLRYNLM 300
  301 GSVISSTSLD GTLRSWKSLF VNQWVKLSEM NVDDYVPSPE EVRAFISSKT TERLPSQLEK 360
  361 TYF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.154902
Match: 1vyhC
Description: PAF-AH Holoenzyme: Lis1/Alfa2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 1.95667720244696 bayes_pls_golite062009
nucleic acid binding 1.90457914882449 bayes_pls_golite062009
GTPase activity 1.66665311782591 bayes_pls_golite062009
snoRNA binding 1.61553185503007 bayes_pls_golite062009
ubiquitin-protein ligase activity 1.59258100795958 bayes_pls_golite062009
DNA binding 1.38475369554616 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
transporter activity 1.21549336905926 bayes_pls_golite062009
protein transporter activity 0.964340340346761 bayes_pls_golite062009
transcription factor activity 0.804334981068351 bayes_pls_golite062009
substrate-specific transporter activity 0.734793983890004 bayes_pls_golite062009
structural molecule activity 0.721739615005709 bayes_pls_golite062009
molecular transducer activity 0.577438981735303 bayes_pls_golite062009
signal transducer activity 0.577438981735303 bayes_pls_golite062009
transcription repressor activity 0.560226369775279 bayes_pls_golite062009
acid-amino acid ligase activity 0.535041400676017 bayes_pls_golite062009
0.53274018413176 bayes_pls_golite062009
transcription factor binding 0.412844855996155 bayes_pls_golite062009
cytoskeletal protein binding 0.359536347486199 bayes_pls_golite062009
receptor activity 0.322599767074871 bayes_pls_golite062009
transcription cofactor activity 0.19391619547146 bayes_pls_golite062009
hydrolase activity 0.181211933860468 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.168317261786777 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.132660456600365 bayes_pls_golite062009
kinase activity 0.127621956173205 bayes_pls_golite062009
transcription corepressor activity 0.00954741955203087 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

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