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View Structure Prediction Details

Protein: CE14894
Organism: Caenorhabditis elegans
Length: 793 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE14894.

Description E-value Query
Range
Subject
Range
gi|148658115, gi... - gi|148658115|ref|YP_001278320.1| NB-ARC domain-containing protein [Roseiflexus sp. RS-1], gi|1485702...
754.0 [0..10] [789..730]

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Predicted Domain #1
Region A:
Residues: [1-97]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEPIKEIAA KRSVEAVYTG GTVRWSANGQ KLFSTCTNVV KVIDLADNTA SYTIGDPEDE  60
   61 LRITCTAVDK NRNRLLVAYN NQIIREYSIP LDPSTTK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.0
Match: 1erjA
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [98-636]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PELARTWKTI HTAPILVMEF NEEGHLLATG SADHIVKVWN LTEQQCTHTL KGPSVVSAIL  60
   61 FGKHEKLVVG YIEGQLNLYN IMRGAPKKLV NTWKSHNSHI TALLQVPDSR VVVALSRDQT 120
  121 MSIHETETQE TLRVLPLYES IEGGAIGHNG NLFTVGEEGV VKEFVIETAK LVRKKRIASS 180
  181 NLDHLAYDVV SNRFLAISAE QNLIILDFEN LKIARQIVGF HDEIYSCCLL GKDESHMAVA 240
  241 SNTSEIRLYN TKTLDCQLIR GHTESVLSVV SPTWDTSLLA SCSKDNSIIF WRLVTSPEND 300
  301 SCSTLVPVAA ATGHANTVTA LAISNTGRAP FLASVSTDCT IKLWGLGVST KLKEVKIDAE 360
  361 KDFVEQLPKL TCSSTMVAHG KDVNCVDISE SDALIATGGM DKLVKLWQVD THKMQLGIAG 420
  421 TLSGHRRGVG DVKFAKNSHK LASCSGDMTI KIWNISEKSC LQTISGHSCA VFRVIFARND 480
  481 SQLISADSAG IIKIWTIKTA DCECSIDAHT DKIWSLSKNH NESEFVTAGT DGRIVVWKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 61.221849
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
snoRNA binding 6.03079504484743 bayes_pls_golite062009
structural molecule activity 5.05435272846365 bayes_pls_golite062009
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
3.41022148055944 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.25521258308263 bayes_pls_golite062009
RNA binding 3.0829625416797 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
cytoskeletal protein binding 2.20122168933317 bayes_pls_golite062009
transcription repressor activity 2.03485691549401 bayes_pls_golite062009
transcription regulator activity 1.95667720244696 bayes_pls_golite062009
nucleic acid binding 1.90457914882449 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
actin binding 1.40054662654509 bayes_pls_golite062009
DNA binding 1.38475369554616 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
transcription corepressor activity 1.2107661925348 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
tubulin binding 1.10875870970504 bayes_pls_golite062009
microtubule binding 1.03769395387791 bayes_pls_golite062009
dynein binding 0.99104010024574 bayes_pls_golite062009
transcription factor activity 0.804334981068351 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
receptor binding 0.498471793965061 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.426429095658617 bayes_pls_golite062009
transcription factor binding 0.412844855996155 bayes_pls_golite062009
kinase activity 0.387572734234845 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.226335610368636 bayes_pls_golite062009
ligase activity 0.20682813699621 bayes_pls_golite062009
transcription cofactor activity 0.19391619547146 bayes_pls_golite062009
chromatin binding 0.190739938818992 bayes_pls_golite062009
mRNA binding 0.0519838181830878 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [637-793]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VTEEKQKAED NKRREAIEQD QTLTNLLSQK RYSEALVFAL TLAKPFCAFK VINALMAEET  60
   61 PEELGSAIRR LDTRQIEILL QFTVKWNTNS RTSSVAQRVL YEIVHIVDPE ELVSMPGAYG 120
  121 YIESFLPYTQ RHMDRLDRAK QDVSLFDFVW RQMRSSV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.39794
Match: 2gnqA
Description: No description for 2gnqA was found.

YRC Informatics Platform - Version 3.0
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