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View Structure Prediction Details

Protein: mut-2
Organism: Caenorhabditis elegans
Length: 441 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mut-2.

Description E-value Query
Range
Subject
Range
gi|73946411 - gi|73946411|ref|XP_856166.1| PREDICTED: similar to zinc finger, CCHC domain containing 6 isoform 8 [...
260.0 [0..7] [429..957]

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Predicted Domain #1
Region A:
Residues: [1-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQPNKDQRS PEDIDFKVKA NPKAFHKFNG KFQRVLRDHE DDFNILSISM QDHFDTTKQP  60
   61 KEEFGKKMDW CYQLKNIISK NNPTWLFNIV PTGSTVTGLA TKNSDLDVAI HIPQAARVLE 120
  121 QEERGRNITD DERQASWREI QLEILQIVRL NLQNDEQINS RINWEHGIQL VQAQIQILKV 180
  181 MTVDGIDCDI SVVMDRFLSS MHNSFLIRHL AHIDGRFAPL CAIVKQWAAS TKVKDPKDGG 240
  241 FNSYALVLLV IHFLQCGTFP PILPNLQEIF KKDNFIAWDD KVYPSILNFG APLPKPLPRI 300
  301 APNNAPLARL FIEFLYYYSM FNFKENYIGA RPVMVMDRRT SQNNMVRSST NKEVCIQDPF 360
  361 DEHNPGRTVR TLNRIKDVMR STYQKFLPVE GSEFTFPTLD DIINMSPEVP KPSRAEVRNF 420
  421 RAEATEVNRV GLGVYCRNSF V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 57.69897
Match: 1f5aA
Description: Poly(A) polymerase, middle domain; Poly(A) polymerase N-terminal, catalytic domain; Poly(A) polymerase, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.122769147009 bayes_pls_golite062009
nucleotidyltransferase activity 0.92178707322923 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.667889614569279 bayes_pls_golite062009
transferase activity 0.63270331673446 bayes_pls_golite062009
nucleic acid binding 0.61402842331964 bayes_pls_golite062009
binding 0.141303651743105 bayes_pls_golite062009
DNA binding 0.0812916917650832 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle