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View Structure Prediction Details

Protein: CE08947
Organism: Caenorhabditis elegans
Length: 590 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE08947.

Description E-value Query
Range
Subject
Range
gi|73981135 - gi|73981135|ref|XP_849121.1| PREDICTED: similar to Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB...
713.0 [0..26] [588..103]

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Predicted Domain #1
Region A:
Residues: [1-121]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTVRFNKQA LAILAACFIF LLCVVCYFSA SSESHNAVVV GERARGHIAV RDVENRHLAE  60
   61 EKHAVIHAKT VGKIERVVSQ EKVEILRPAR VESKPPGEKT STEPEETGVG KAPIQTSEGL 120
  121 E

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [122-590]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLIGKIHYEN KDEENDLRRQ KVKEMMIHAW EGYKNYSWGA NELRPMSKKP NSQNIFGGSQ  60
   61 MPATIVDAAD TLFIMDLKDK YKEARDYIEN NFSMAKSTST LSVFETTIRF LGGLLSLYAL 120
  121 TQESFYIEKA REVGEALLPA FNTPSGIPKS NLDVASKHAS NYGWANGGQS ILSEIGSLHL 180
  181 EFLYLSRISN APIFEKKVKK VRDALEKAEK PNGLYSNYIN PDTGKFTGSH MSLGALGDSF 240
  241 YEYLIKSYVQ SNYTDTQAKN MYWDVSDAIQ KHMIKVSKQS NLTYTVELNN GQAQHKMGHL 300
  301 ACFVPGMFAL QAINEDTEEE KLRIMTLAEE LAKTCHESYI RSETHIGPEM FYFNERDEAT 360
  361 SKHSENGYIQ RPEVIEGWFY LWRLTGKTMY RDWVWDAVQA IEKYCRVDSG FTGLQNVYNP 420
  421 KAGREDVMQS FFLAEFLKYA YLTFADESLI SLDKWVFNTE AHPVPVLTN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 1nxcA
Description: Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyl-oligosaccharide mannosidase activity 7.089685350864 bayes_pls_golite062009
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 6.95179264736435 bayes_pls_golite062009
mannosidase activity 5.20286438265852 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 4.31319275372149 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 3.65589746311782 bayes_pls_golite062009
hydrolase activity 2.67964748309919 bayes_pls_golite062009
binding 1.49199031708525 bayes_pls_golite062009
catalytic activity 1.31873306707813 bayes_pls_golite062009
cation binding 0.362242764130218 bayes_pls_golite062009
metal ion binding 0.362242764130218 bayes_pls_golite062009
protein binding 0.36081692928767 bayes_pls_golite062009
ion binding 0.355220167272296 bayes_pls_golite062009
calcium ion binding 0.121126738064555 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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