YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: egl-3
Organism: Caenorhabditis elegans
Length: 652 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for egl-3.

Description E-value Query
Range
Subject
Range
gi|109463670 - gi|109463670|ref|XP_001078022.1| PREDICTED: similar to Proprotein convertase subtilisin/kexin type 5...
447.0 [0..2] [634..197]

Back

Predicted Domain #1
Region A:
Residues: [1-130]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNTHVDLIC VFLSIFIGIG EAVDVYTNHF HVHLKEGGGL EDAHRIAKRH GFINRGQVAA  60
   61 SDNEYHFVQP ALVHARTRRS AGHHAKLHND DEVLHVEQLK GYTRTKRGYR PLEQRLESQF 120
  121 DFSAVMSPSD 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.39794
Match: 2p4eP
Description: No description for 2p4eP was found.

Predicted Domain #2
Region A:
Residues: [131-652]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLYGYQWYLK NTGQAGGKAR LDLNVERAWA MGFTGKNITT AIMDDGVDYM HPDIKNNFNA  60
   61 EASYDFSSND PFPYPRYTDD WFNSHGTRCA GEIVAARDNG VCGVGVAYDG KVAGIRMLDQ 120
  121 PYMTDLIEAN SMGHEPSKIH IYSASWGPTD DGKTVDGPRN ATMRAIVRGV NEGRNGLGSI 180
  181 FVWASGDGGE DDDCNCDGYA ASMWTISINS AINNGENAHY DESCSSTLAS TFSNGGRNPE 240
  241 TGVATTDLYG RCTRSHSGTS AAAPEAAGVF ALALEANPSL TWRDLQHLTV LTSSRNSLFD 300
  301 GRCRDFPSLG INDNHRDSHG NCSHFEWQMN GVGLEYNHLF GFGVLDAAEM VMLAMAWKTS 360
  361 PPRYHCTAGL IDTPHEIPAD GNLILEINTD GCAGSQFEVR YLEHVQAVVS FNSTRRGDTT 420
  421 LYLISPMGTR TMILSRRPKD DDSKDGFTNW PFMTTHTWGE NPTGKWRLVA RFQGPGAHAG 480
  481 TLKKFELMLH GTREAPYNLI EPIVGQTNKK LDTVQKAHKR SH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 91.39794
Match: 1p8jA
Description: Furin, C-terminal domain; Furin, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nerve growth factor binding 5.17216805931457 bayes_pls_golite062009
peptidase activity 4.77677490610016 bayes_pls_golite062009
neurotrophin binding 4.47215080222714 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 4.40501322467328 bayes_pls_golite062009
serine hydrolase activity 4.30899317351154 bayes_pls_golite062009
serine-type peptidase activity 4.29545891350519 bayes_pls_golite062009
endopeptidase activity 3.83336601331518 bayes_pls_golite062009
serine-type endopeptidase activity 3.71508033196614 bayes_pls_golite062009
hydrolase activity 2.05732080397524 bayes_pls_golite062009
protein binding 1.53121577002039 bayes_pls_golite062009
cell surface binding 1.35082641853563 bayes_pls_golite062009
binding 1.28749522568113 bayes_pls_golite062009
receptor binding 1.25719003525894 bayes_pls_golite062009
heparin binding 0.876342157478361 bayes_pls_golite062009
protease binding 0.70588409047823 bayes_pls_golite062009
eukaryotic cell surface binding 0.64950741809726 bayes_pls_golite062009
catalytic activity 0.597535457699629 bayes_pls_golite062009
glycosaminoglycan binding 0.57147918956324 bayes_pls_golite062009
growth factor binding 0.543263320403739 bayes_pls_golite062009
exopeptidase activity 0.42083764849682 bayes_pls_golite062009
polysaccharide binding 0.10343618041863 bayes_pls_golite062009
low-density lipoprotein receptor binding 0.0535137917871995 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle