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View Structure Prediction Details

Protein: CE08817
Organism: Caenorhabditis elegans
Length: 544 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE08817.

Description E-value Query
Range
Subject
Range
RPC3_BOVIN - DNA-directed RNA polymerase III subunit RPC3 OS=Bos taurus GN=POLR3C PE=2 SV=1
604.0 [0..5] [542..3]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGGGKYETQM CVIIIEDIFG KIVAKVMETI LKESCQLSTL FYKLKGQISN TLIRKSVSTL  60
   61 INFGFVTFHL DTNNRTTYVA DSDQIQHVIS SPRACLIAKT LYGPAAESIC VELISQGRLT 120
  121 VSETIRRIQ

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 21.522879
Match: PF08221.2
Description: No description for PF08221.2 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [130-291]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATDETAVFSD IKKSFEELAA AHFLIRVPSV ESEIHGCPQF VTNFDPFAIS TNIMEKKEGT  60
   61 STSDSTSNNR KRKADSTPED GDAGQYWRIN WIRFNGYLRD ELIIDYLIGG GSKGTMTNLN 120
  121 VKKEETIEDP QGDRTQYITQ NVAHLMFKIN ETRAKPMSME SI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [292-471]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TASLTDLQRL VKENGLNLAK PDIELACQIL VDESDGIIRK LGESNGGIFI VDIRRAIRQI  60
   61 CRHHCESLIR EQFEGRAIRV MRLLENRHYL DEEQVEKLSM MSGKEAREML YALVEEGYVF 120
  121 NKPVGRSNDF QPARTFYLYY VDLPRTIRGL VEYTCKLVRN LIVRQRHERT ENKSVLDKDA 180
  181 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1q1hA
Description: An extended winged helix domain in general transcription factor E/IIE alpha
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 5.55329976718261 bayes_pls_golite062009
DNA binding 5.08959163553491 bayes_pls_golite062009
nucleic acid binding 4.99681957904233 bayes_pls_golite062009
RNA polymerase activity 4.38040357248614 bayes_pls_golite062009
DNA-directed RNA polymerase activity 4.38040357248614 bayes_pls_golite062009
transcription factor activity 4.33152142980289 bayes_pls_golite062009
binding 3.52874320222492 bayes_pls_golite062009
nucleotidyltransferase activity 2.80876790343695 bayes_pls_golite062009
sequence-specific DNA binding 2.48053910222825 bayes_pls_golite062009
transcription activator activity 2.37668609508629 bayes_pls_golite062009
transcription repressor activity 2.22485867684613 bayes_pls_golite062009
transferase activity 2.17455387041569 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.13327310661537 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.70025468248325 bayes_pls_golite062009
transcription factor binding 0.85714789329232 bayes_pls_golite062009
protein binding 0.753698599635855 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.461477365615935 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.0856082199488197 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [472-544]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVQPIIENIR SSEQLDEASK LAQIAEVEEM YLPGPDRAQL NRFRKAQATL LAAQDQSIRV  60
   61 LLSFKLFLAS GEN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle