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View Structure Prediction Details

Protein: CE08730
Organism: Caenorhabditis elegans
Length: 469 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE08730.

Description E-value Query
Range
Subject
Range
gi|47211485 - gi|47211485|emb|CAF95090.1| unnamed protein product [Tetraodon nigroviridis]
350.0 [0..10] [467..19]

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Predicted Domain #1
Region A:
Residues: [1-361]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNNETEPDV IKRIIGYYIQ KESSEISTVG LSRLTHAVFG SLRVQLNGTF EIGNAFSKRK  60
   61 FKNWQRAVKN SSSNVKSMIS IGRWDSVTQL SSVLLNVKSR RMFIESIVDF LKEHQLDGID 120
  121 LFWRWVPLAV QSEFCLFLEE VKIEFLNQEK QYILSITAPP VGIENYEDGY DIEEIIERVD 180
  181 FVNVYSMNYA APWSNQWGTP TGPSAPLYGG LDARRKFSVD YTMKYYIRYT RKPEKFNLII 240
  241 PFYVRHWRNV ENAIKPGIEV FRNVTLQNNG AIGEVYMSRW TAESDGIELS NPSWDDTTKT 300
  301 LYIWKPETKT FITFETEKSI EAKANYVKSM NLGGVWIWLM ENDDQDNSMI EAVSGQFGNP 360
  361 S

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.69897
Match: 1wawA
Description: Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against human chitinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
chitinase activity 6.40555694403866 bayes_pls_golite062009
hydrolase activity, hydrolyzing O-glycosyl compounds 1.91170236789651 bayes_pls_golite062009
growth factor activity 1.90639563461312 bayes_pls_golite062009
receptor binding 1.65049220192308 bayes_pls_golite062009
amylase activity 1.38959979746158 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 1.34796838721403 bayes_pls_golite062009
chitin binding 1.29046765706168 bayes_pls_golite062009
carbohydrate binding 0.83219070974164 bayes_pls_golite062009
imaginal disc growth factor activity 0.779343156561511 bayes_pls_golite062009
binding 0.720909632154373 bayes_pls_golite062009
protein binding 0.648259867811962 bayes_pls_golite062009
pattern binding 0.629401292223251 bayes_pls_golite062009
catalytic activity 0.534516847146079 bayes_pls_golite062009
glucosidase activity 0.50219358960551 bayes_pls_golite062009
hydrolase activity 0.178746202646272 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.121443733937724 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [362-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDQSQYEHVS DKRIIGFYTE DATTEITASE LSKLTHAVFG FLYLKTNGTF DILNDRGKGR  60
   61 FKNLNRLIKY ENLNVKMMFS IGGWADSTNF RSVVADVKIK RFEILNYF

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.59
Match: 1kfwA
Description: Psychrophilic chitinase B
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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